11/12/2025

speaker
Michael Christodoulou
Head of Investor Relations

Well, good morning and welcome to our media update for the third quarter. Many thanks for joining us today. Bill Anderson will kick us off with the year-to-date business performance and an update on strategic priorities. Wolfgang Nickel will then provide more details on the financials and outlook. And after that, we will have time for your questions. And now, before starting, I would like to briefly draw your attention to the cautionary language included in our safe harbor statement. And with that, over to you, Bill.

speaker
Bill Anderson
Chief Operating Officer

Thanks, Michael. Thanks to all of you for joining today's call. So we posted our results for the third quarter earlier today. And as you saw, sales are slightly up in currency and portfolio adjusted terms, both in the quarter and year to date. So you'll note that we refer to currency and portfolio adjusted sales growth figures throughout today's presentation. Core EPS is at 4 euros and 29 cents, up 7% from last year. And free cash flow is at negative 800 million, which is in line with our projections and the seasonality of our business. So here's what the picture looks like in our divisions. First, crop science. Q3 is always a smaller quarter for our agriculture business, but crop science continued to show resilience. Sales are slightly down nine months into the year, with the significant regulatory effects that we're absorbing. Corn is up 9% this year, with solid Q3 growth coming from increased acreage in the U.S. and a strong start to the LATAM season. Our core crop protection business was down 2% in Q3 on the expiration of Movento's Europe license. Glyphosate, which we steer separately, posted slight Q3 growth on account of pricing. On the bottom line, we're realizing efficiency gains from our operating model and profitability measures. While Q3 had some favorable phasing, we're very well positioned to deliver our commitments for the full year. Moving on to pharmaceuticals, we remain encouraged by the resilience of our top line. Both Nubeka and Corendia continued their impressive momentum, with Nubeka up 60% year over year and Corendia up nearly 80% in the same timeframe. Thanks in particular to strong growth in the U.S. and China. ILEA declined in Q3. We saw significant pricing pressure in both Japan and Canada, as well as some one-time effects. But we remain confident in our ambition to keep 2025 ILEA sales stable relative to 2024. Our year-to-date EBITDA margin is at 26.1%. This is down slightly from last year due to pricing pressure, currency effects, and investments into our launches, but we're on track to land within the guidance we upgraded in summer. In consumer health, we see an increasingly challenging market environment, particularly in U.S. and China. In that context, our year-to-date growth is currently behind our full-year projection due to the soft market environment. We expect those dynamics will put further pressure on our top-line growth in Q4, so we're lowering our 2025 sales growth expectation for consumer health. Regardless of how the market develops, we're committed to delivering an EBITDA margin in line with our guidance of 23 to 24 percent and continued strong cash contributions. Overall, in a pivotal year, we're in a strong position to deliver the 2025 group guidance that we upgraded last quarter. There's more to do this year and beyond. Looking at 2026, we look forward to continued growth from Nubeka, from Corendia, and the first meaningful sales from Biantra and Linquet, which we just received FDA approval for. We remain confident that our dynamic shared ownership system will deliver continued efficiency gains in line with our commitments. And we're aware that we have challenges to navigate, including declines in Xarelto sales, currency headwinds, and some trade uncertainty. However, overall, we're confident in our improvement plan and the trajectory of our business. We're finalizing our assumptions and we're gonna provide more transparency on 2026 in our call on 2025 full year results in February. Now let's take a look at our strategic agenda. I'll mention a few of the highlights captured on this slide. On our pharma pipeline, we announced FDA approval of Linquet just two and a half weeks ago, and we expect it to reach the US market this month. Further, we're making good progress with our cell and gene therapy assets against Parkinson's, which are now in phase three and phase two, respectively. In addition, we just announced study data for corendia in patients with chronic kidney disease associated with type 1 diabetes, making it the first medicine in over 30 years to demonstrate positive results in addressing the high risk of kidney disease progression and cardiovascular events in this patient population. In litigation, as each prong of our strategy advances, we have a clearer view of the paths to significant containment. I say paths, plural, because there isn't just one way to get there, and no one way alone will be enough. We're making significant progress, and we are confident in our objective to significantly contain litigation risk by the end of 2026. Here's where we stand. I'll start with PCBs. We recently received an adverse verdict on the PCB Erickson case by the Supreme Court in the state of Washington. This verdict confirms that our earlier decision to reach settlements on the remaining Sky Valley cases was the right one. Nonetheless, we disagree with that decision and we concur with the dissenting justices who found the court's opinion judicially inconsistent on the statue of repose issue. We're considering further legal options for that specific case. And overall, we'll continue to consider all options to limit the company's risk exposure. In the glyphosate litigation, we're expecting a recommendation from the US Solicitor General as to whether or not the US Supreme Court should hear our case. We remain optimistic that this recommendation will occur in time for the current session, which ends in June of 2026. This is an important decision, and we have plans in place for all outcomes. In the legislative realm, we continue to believe that U.S. farmers need certainty. That's particularly true in times of challenging farm economics. At the federal level, both the Appropriations Bill and the Farm Bill are important pieces of legislation that reinforce clarity on how essential crop protection tools are regulated in American agriculture. The government shutdown has delayed congressional activity, and it's essential that progress is made. And we're making that case. At the state level, another round of legislative sessions will soon kick off, beginning in January. We think it's very important to defend the work of American farmers, and we will advocate for the innovation and regulation that they need. Overall, we know that we have a crucial and highly dynamic phase ahead of us. You see this dynamic reflected in our provision, which moved over the past quarter due to a range of factors. For example, after Q2, we announced some confidential settlements, which were followed by a moderate increase in glyphosate case filings. It's natural that the prospect of settlements would prompt an increase in the case count, and we expect that to continue as our containment efforts mature. The case count leads to additional provisions, as do the costs of litigation. At the same time, we've reached settlements on some verdicts at both the appeals and post-trial motion phases, because settling them was advantageous in limiting the company's exposure. Finally, the recent PCB Erickson verdict led to an upward adjustment of our provision. I share that background because it's emblematic of what we expect in the coming phase. Consequential decisions, some in our control and others not, with important bearings on our path forward and the future of glyphosate in American agriculture. We're convinced our multi-pronged strategy is the right one. As we continue to advance it, we'll continuously adjust our approaches to resolution, evaluating them for their future optionality, finality, cost, and risk. On cash and deleveraging, we saw a further reduction in net financial debt in Q3, and we confirm our full-year free cash flow outlook, including litigation-related payouts. Our crop science organization is aggressively focused on execution of our five-year plan. We're actively streamlining our portfolio and operations by outsourcing 12 active ingredients and discontinuing 150 products. This strategic focus enables us to concentrate on innovative crop solutions. A prime example is our recent launch of Planexus. It's a cutting-edge insecticide which hit the Latin American market last week. Finally, on our operating model, we see benefits on the top and bottom line. Our organization continues to get leaner and more efficient, and we're seeing benefits in terms of speed and focus. I'll close with an example from our pharmaceuticals division. 20 months ago, we announced a deal to in-license Biantra in Europe. Prior to that, this medicine wasn't on the radar for many people in the company. But by April of this year, we had launched it in Germany, and the first European patients were able to receive Biantra. Today, the medicine is off to a strong start, already exceeding our ambitions for 2025. Only months into the launch, we've reached around 50% market share in new-to-brand prescriptions in Germany, one of the fastest uptakes of a cardiovascular treatment we've seen. The teams are now focused on making Biantra the new standard of care in its treatment setting. And they attribute their speed and success in part to their ability to cut out inefficient handovers, flexible resource allocation across markets, and a keen focus on most important work. With that, I'll hand it over to Wolfgang. But before doing so, you've seen we announced Wolfgang's successor last week. Judith Hartman will be joining Bayer in March of next year, and she'll take over as CFO on June 1st. Judith brings with her a wealth of finance and leadership experience across industries and countries, and we look forward to welcoming her. It's far too early to say goodbye to Wolfgang, who will be retiring in June of next year, as we've previously communicated. We've got a crucial period ahead for the company, and he's going to be dialed in on delivering 2025, planning 2026, and continuing our efforts to significantly contain litigation. Wolfgang, I look forward to continuing to work with you over these next months. Thank you so much, Bill.

speaker
Wolfgang Nickel
Chief Financial Officer

Appreciate it. Hello and also welcome from my side. Let's go right into it and look at the group picture for Q3 first. Net sales grew by 1% versus the prior year quarter in currency and portfolio adjusted terms. As reported, we saw a decline of 3% with continued foreign exchange headwinds affecting our top line with about 450 million euros. In a seasonally low quarter, EBITDA before special items of 1.5 billion euros came in 21% above the prior year. The increase was largely driven by better crop science and reconciliation results, offsetting slight decline in pharma. Let me pause right here and give you some more background on the reconciliation line. It includes a rather predictable element for our enabling function costs that cannot be clearly allocated to the divisions. In addition, there are other elements, mainly around incentive provision, side businesses, such as our soccer club and balance sheet-related hyperinflation effects, that are more unpredictable. These factors can vary significantly from quarter to quarter and versus the prior year periods. For Q3, the main drivers versus last year were lower expenses for personnel related adjustments and lower hyperinflation effects, while additions to long-term incentive provisions were comparable to the prior year. For the full year, we anticipate favorability-enabling function costs on top of positive one-offs in our side businesses. While some elements can still move, we now expect around minus 400 million euros for 2025 and an improvement of about 100 million euros versus our previous guidance. Core earnings per share for Q3 came in at 57 cents and they were above the prior year quarter and that delta was 33 cents. It was largely due to the higher EBITDA as well as better core financial result. The core financial result improved by about 56 million euros year on year, largely driven by lower interest expenses due to lower debt. Earnings per share came in at minus 98 cents for the quarter. Main driver for the delta from core to reported earnings per share next to the regular amortization of intangibles are additional litigation-related provisions classified as special items in the total amount of 934 million euros. These include amounts for the glyphosate litigation reflecting an increased case count, other litigation costs, and the settlement of some cases which were strategically advantageous to resolve, as Bill mentioned just a minute ago. We've also adjusted the provision for the impacts from the recently received PCB Erickson ruling in the Washington Supreme Court. Our free cash flow came in about €0.6 billion for Q3. The delta versus the prior year is mainly driven by higher settlement payouts. Compared to the end of Q2, net financial debt decreased by about €600 million to €32.7 billion, mainly due to the operational cash inflow. Year on year, net financial debt was down by about €2.3 billion. Based on the year-to-date performance, we feel confident in the full year outlook for crop science and pharmaceuticals, both in terms of top and bottom line. For the fourth quarter, we expect to see the following developments. For crop science, growth in the fourth quarter is driven by glyphosate, which is now anticipated at the upper end of our full year sales guidance range and will have a dilutive impact to margin in Q4. In addition, growth is anticipated for Latin America, recovering from a week prior year period. For our pharma business, we anticipate increased price pressures for ILEA in conjunction with the entry of two milligram biosimilars in Q4. In addition, we expect continuous generalization of Xarelto as well as volume-based pricing-related impacts on our business in China. The continued growth of our launch assets is expected to compensate for these headwinds. On our margin, we expect to see accelerated launch investments in Q4, for example linked to our liquid launch activities. For consumer health, we have already pointed to the lower end of our sales growth guidance range for the full year at our Q2 call in August. Given our significant exposure to markets with challenging dynamics like the U.S. and China, we now expect full-year sales growth for consumer health in the range of minus 1% to plus 1%. This does not impact the group outlook. In close partnership with retailers, we will carefully manage the balance of sell-in and sell-out to ensure sustainable growth going forward. In terms of profitability, we are committed to achieve the expected EBITDA before special items margin range of 23 to 24% for the full year. Based on months and September rates, we see similar foreign exchange effects for all three divisions compared to prior guidance. Let me conclude with the group outlook for 2025 and early insights into the business drivers for 2026. Overall for the group, we confirm our full year 2025 outlook at constant currencies and the latest currency estimate, which did not change materially from month end June to month end September rates. At the same time, we update our modeling assumptions for special items for the additional litigation-related provisions we booked this quarter. We now expect special items in the range of minus 3.5 to minus 4 billion euros for the full year. We also adjusted the recon modeling assumption, as I mentioned earlier in my remarks. Let's now look at 26. For Pharma, we will continue to ramp Nubeka and Corentia, scale Beyondra and launch Linquid. For Xarelto, we expect declines in a similar percentage range as this year. For ILEA, we will gain further insights into the evolving market dynamics with an aspiration to drive volume growth of the 8 mg dosage. For crop science, the ag market outlook is quite dynamic. We are monitoring acreage development, particularly in the context of geopolitical uncertainty. In corn, we plan to drive growth based on our portfolio refresh and build on continued technology adoption. For soy and cotton, we count on the registration for dicamba for the next season. Overall, we remain intensely focused and on track to deliver our five-year framework. For consumer health, while we experience some challenges in key markets this year, we see the general market growth trends intact. We will keep investing in our brands to address consumer needs and drive consumption through household penetration. On geopolitics, we have gained some more clarity on EU-US pharma tariffs. In recent weeks, individual companies have announced drug pricing deals, but some questions, particularly around sectoral pharma tariffs or potentially policy shifts in other countries, remain open. At the same time, our cross-functional teams showcased their strengths in managing the situation and limiting potential impact for this year. Looking ahead, we continue to carefully monitor the developments and will include the most likely scenario in our planning for next year. We are also following the US-China trade relations closely as we are innovating for the benefit of our patients, farmers and consumers in all markets. Both the US and China remain mission critical for us. On foreign currencies, this is a major swing factor for our business. As already pointed out previously, we expect significant currency headwinds to continue in 2026. In conclusion, we are fully focused on effectively managing what we control, adjusting to new realities around us quickly and advancing in our transformation. We're currently completing the picture for 26 and will communicate specific guidance with our full year 25 results end of February. And with that, over to you, Michael, to facilitate the Q&A, please.

speaker
Michael Christodoulou
Head of Investor Relations

Thank you very much Wolfgang and Bill. And let's now start with the Q&A session. So here's what you need to do to ask a question. Please make sure that Zoom is the only active chat program open on your computer and make sure that your microphone is activated in Zoom. If that is the case, you can use the raise hand function and we will register your interest. And when it's your turn, I will call your name. A pop-up window will then open on your screen. And when you see this pop-up window, please unmute yourself and ask a question. And your camera will remain off during this time. So much for this. Let's now get started. And let's see, we have a first question coming from Antje Hoening, Rheinische Post, followed then by Aisha Sharma from Endpoint News. But first question goes to Antje Hoening from Rheinische Post. Antje, over to you.

speaker
Antje Hoening
Reporter, Rheinische Post

Hello, good morning. You say that PSO pays off. Can you tell me how many jobs has Bayer cut in this context and how many in Germany? And when will the reorganization and the job cuts be completed? Thank you.

speaker
Bill Anderson
Chief Operating Officer

Yeah. Thanks, Sancha. So so far, we've eliminated about 13,500 jobs worldwide. I don't have a specific Germany number, but I would say that the cuts have been roughly proportional so far. And about 20 percent of our employees are based in Germany. And. Let's see, when will it be over? So we never had a specific job reduction target. We've always said our our approach is to design the whole organization around customers, around products, around the science. and take out all the jobs that are sort of gatekeepers and basically the jobs that unintentionally serve to slow down innovation and make us slower to respond to our customers' needs. And we're going to continue doing that as long as it takes to become the fastest, most innovative life science company in the world. I would anticipate that the most significant reductions have already happened and that going forward, there'll be less than we've seen in the past. Thank you.

speaker
Michael Christodoulou
Head of Investor Relations

Okay. Next question comes from Aisha Sharma from Endpoint News. And afterwards, we have Jonas Janssen from Frankfurter Allgemeine Zeitung. But next question goes to Aisha. Over to you.

speaker
Aisha Sharma
Reporter, Endpoint News

Good morning, and thank you for taking my questions. Just two from me. Firstly, with regards to deals on most favored nation pricing, I know that companies like AstraZeneca have announced deals with the Trump administration saying that they could cut the price of some drugs by up to 80%. I was just wondering where Bayer is in terms of its talks, and is it considering the same sort of range of price cuts? And secondly, just on your menopause drug that was recently approved in the US, I was wondering what makes you confident that that's going to have a strong commercial launch? Just because other drugs like Estella's Vioza have had a bit of a difficult start, lower than expected commercial demand and some issues with the reimbursement. What makes you confident that this will be different? Thank you.

speaker
Bill Anderson
Chief Operating Officer

Yeah. Thanks, Aisha. Yeah. First, regarding MFN and deals, we yeah, we've been monitoring the situation very closely. We have a very strong presence in the US. We already have very substantial discounts on most of our portfolio. And we're Yeah, we don't have anything new to to discuss on that right now. But we we think we offer a very strong value for American consumers and patients. And we intend to continue that. And but we stay we stay very close on that topic regarding Linquit. Yeah, we're really pleased with the strong label we received. This is a. Yeah, a really good molecule. It has sort of two mechanisms of action, which we think may be a differentiator. It works on hot flashes, but also reduces nighttime awakenings, which is a significant issue for women in menopause. And yeah, we have decades of work in women's health, and we will bring that expertise and that knowledge of the field to our efforts to make sure that women have that option. So, yeah, we look forward to a strong launch and further updates for you in the future.

speaker
Michael Christodoulou
Head of Investor Relations

Okay. Next question comes from Jonas Janssen, Frankfurter Allgemeine Zeitung. Afterwards, we have Kevin Grogan from Script. Jonas, you're next in line. Over to you.

speaker
Jonas Janssen
Reporter, Frankfurter Allgemeine Zeitung

Good morning and thank you for the chance to ask a question. Regarding the provisions for the litigation complex, it's now again another roughly a billion. Do you think that this will be enough looking to the future or do you sometimes think you needed to do like a bigger number again? to not every other quarter say, yeah, we need to put a little more money to that to have this, yeah, this feeling that this still never ends. Thank you.

speaker
Wolfgang Nickel
Chief Financial Officer

Yeah, Jonas, good morning. Very, very good question. When it comes to the provision, we are bound by the accounting rules like any other company is. And you have two conditions. A amount needs to be predictable. um and it needs you need it needs to be probable so you need to be able to put a number to it and it needs to be more likely than not and as we advance in resolving the litigation by the end of next year substantially containing it more pieces of the puzzle so to speak become clear you have seen that after q2 we'll put a substantial provision associated with settlements uh in both glyphosate and and uh also a in PCBs on the balance sheet. We've done the same thing last quarter where we added just over 900 million to the provision because we made progress again on glyphosate. You have seen that we had to provide for new cases but that we also did some strategic settlements last year. So it's hard to predict what's going to follow it. It comes together with resolving the overall complex. And as Bill said earlier, we're making substantial progress there on all the four prongs of our strategy. And stay tuned. We will report more on that as we go. Thank you for your clarification. You're welcome, Jonas.

speaker
Michael Christodoulou
Head of Investor Relations

Okay, so if you do want to ask a question, use the raise hand function. And the next one is Kevin Grogan from Scrip. Kevin, over to you.

speaker
Kevin Grogan
Reporter, Scrip

Good morning, everybody. Hope everything's marvellous. Quick question first on Beyondtra. Obviously, it's gone off to a very good start, very impressive. And you're very infused, obviously, Bill, about the way that your teams have managed the launch. Does that experience tempt you to go shopping again for some sort of late stage asset, given that your team has shown that they know how to do a good launch? and would you be interested in licensing something else there's quite a few interesting late stage assets around and just a quick one also on Corendia again given the very strong sales growth and the recent positive data and kidney and so on could you give me an idea of what you think peak sales will be given that you've made a forecast before but it's going maybe better than expected thank you

speaker
Bill Anderson
Chief Operating Officer

Yeah, thanks, Kevin. And also thanks for the extra energy contribution. It seems like you've had your coffee this morning and I'd like to get some of whatever you got. Yeah, Biantra, as I said, we're very pleased with the launch. And you asked whether we're, you know, sort of shopping again. And I would say we're always on the lookout for good value. across every stage of the pipeline. Now, as you probably know, good value is a lot harder to come by in the late stage. And in fact, I would say, yeah, probably 75 to 80 percent of late stage deals end up being negative NPV deals. and for, for the acquirers. And, uh, I've, you know, I've been in the industry almost 30 years and actually I don't like doing negative NPV deals. So, uh, for that reason, you know, we, we have very, very high hurdles. And I think Bianca is a good example of being, uh, careful and diligent and getting a good value. I recently asked for information on new Becca, um, the, the original new Becca deal. We, we had a 50 million, uh, Fifty million dollar upfront on that. And that was a phase three ready deal. And it was a it was a product that, you know, I think people were underestimating and we saw something in it. And, you know, Nubeka is is well on its way to being a mega blockbuster. So we're going to do more of those kinds of deals, but they don't come along every day. And we're going to be very choosy because I don't want to join the ranks of many other pharmaceutical companies that are in the, you know, they have the winner's dilemma where they won the prize, but they lose on the economics. Corendia, you said it. I mean, we're... continue to be very pleased by the data that's coming in. So as you know, we got the heart failure indication this year, and we're beginning to promote that now around the world, and that's really fueling the sales increase. But we just got this data on people with type 1 diabetes and kidney disease, and again, seeing a really excellent result. So, yeah, we look forward to many more happy patients with Corendia. But we don't give peak sales. So we're, yeah, our goal is make sure that all the patients in the world who can benefit from Corendia get it.

speaker
Michael Christodoulou
Head of Investor Relations

Thank you. Okay, so we have Annette Becker from Börsensaitung next, and then followed by Sonja Wind from Bloomberg.

speaker
Annette Becker
Reporter, Börsenzeitung

Annette, first over to you. Yes, good morning.

speaker
Michael Christodoulou
Head of Investor Relations

I hope you can hear me. Yep. Yep.

speaker
Annette Becker
Reporter, Börsenzeitung

I would like to come back to the provisions, especially for PTB cases. Can you tell us the PTB cases, provisions? You increase the provisions. Can you give us a number, how big is your provisions now in the balance sheet? Because in the report, you mentioned that it's 7.2 or 3 for the glyphosate cases? Can you give us a comparable number for the PCP cases? And regarding the negative verdict, can we think that you now try to settle the pending cases that are not in the prior several months until this?

speaker
Wolfgang Nickel
Chief Financial Officer

Yeah, I think I got your question. Thanks. Thanks for that. Total provision on the balance sheet is about 7.8 billion euros. We disclose that just under seven is for glyphosate. And since we don't have any other big cases that require provisions, you can kind of conclude what the PCP portion is. Again, they are the same thing applies that you provision when you can estimate something and when it is More likely than not. And until the summer, you have seen that we provisioned only for defense costs for PCB. And now as the complex resolves itself, you see these provisions coming into the balance sheet. I think we've already said, and Bill referred to it, we were disappointed with the Supreme Court of Washington's verdict. And in particular, as it relates to the statute of repose. We have seen that we put provisions for that case on the balance sheet. We also provisioned for some cross-reads on that. And we'll see what happens with the cases, the verdicts that are still open. Eventually those have to be resolved as well. But I can tell you also this, that we are quite pleased with the fact that we could settle everything that was related to other cases on file. and cases that have not gone and got a court date yet. We're pretty pleased that we got that done beforehand and got also a resolution on some case orders by the court that increased the hurdle on what you have to do in providing evidence up front. So I think we are in reasonable control on the Sky Valley complex.

speaker
Michael Christodoulou
Head of Investor Relations

Okay, and the next questions come from Sonja Wind from Bloomberg. Sonja, over to you.

speaker
Sonja Wind
Reporter, Bloomberg

Hello, can you hear me?

speaker
Michael Christodoulou
Head of Investor Relations

Yes, we can hear you.

speaker
Sonja Wind
Reporter, Bloomberg

Okay, thank you for taking my question. I have a follow-up question on the MFN. question with truck prices. Bill, you mentioned that you already have sizable discounts. Are you referring to the PPM discounts or other discounts that you now implemented as a response to Trump's strategy? And would you consider coming up with your own direct to patient platform or would you rather consider the Trump Rx platform? And then my second question is on the crop science business. You noted that prices for glyphosate increased in North America, but then you pointed that in the fourth quarter, it will be margin dilutive. Could you explain a bit the dynamics that are going on with the prices for glyphosate?

speaker
Bill Anderson
Chief Operating Officer

Yeah, thanks. Thanks, Sonia. And welcome to the world of Bayer. And yeah, on MFN and some of the questions you had about discounts. So we have a wide range of discounts across our portfolio. Some of those are with PBMs or direct with insurance companies. Others are to health care providers. Still others with obviously Medicaid discounts are very important. And we're... Yeah, our goal is to make sure that all the patients who can benefit from any of our products has access. So we'll pursue whatever means we need to to make sure that's the case. And yeah, we'll certainly consider all the platforms that we can use, including new ones that are emerging. Wolfgang, do you want to talk about the margin?

speaker
Wolfgang Nickel
Chief Financial Officer

I can help on glyphosate. What we said, Sonja, is in crop science, we have seen in the glyphosate portion the reference pricing a little bit above the 15-year median, which was driven by the U.S., and there it was driven by specific tariffs that the U.S. imposed on China on this product. What you should also know is that the glyphosate business in our crop science business is very dilutive. We always talked about 200 basis points or so. And therefore, if the growth in Q4 is driven by glyphosate, then it will be dilutive to the overall margin that quarter as well. So it's a quarterly effect from a higher mix of glyphosate relative to the rest of the products.

speaker
Michael Christodoulou
Head of Investor Relations

Right. Thank you very much. Actually, I don't see anyone right now raise the hand. So maybe I just wait for just a few seconds and see what happens. But that's OK. We can also have a kind of a shorter and crisper session today. I'd see Jonas. I think you have a follow up question. So Jonas, over to you.

speaker
Jonas Janssen
Reporter, Frankfurter Allgemeine Zeitung

Yes, thank you very much. Speaking about glyphosate and the margin effects, you reported that the non-glyphosate products are now selling more. What's your expectation in the next few months also regarding alternatives to glyphosate and how is the situation at the moment with the products from China and also maybe with regards to what's happening in Germany, because you had big problems there and closing one plant because of the pricing effects and the whole chemical industry in Germany is suffering, as you, of course, know.

speaker
Bill Anderson
Chief Operating Officer

Yeah. Jonas, thanks. It's a kind of multi-part question. I would just say... The intense price competition on the high volume, especially older and off patent active ingredients, it continues to intensify. And that's why we've basically made a strategic shift. And we're going to go out of a number of those products because there's just simply no profit in the world. And it would appear that a lot of those products are being sold below cost. So that's obviously not a business you want to be in. On the other hand, our newer products and some of our advanced formulations are doing very well. And, for example, we just launched last week, first time in the world, and this is in Latin America, a new insecticide called Planexos. And just to give you a sense of why that's a new dynamic, not only is this product is... effective against a number of insects that older products, the insects have become immune to. Not only that, but it's a very potent and very safe product. The dosage for insect control is six grams per hectare. So, you know, many older products, it's it's sort of like, you know, a kilogram or more per hectare. And now we're talking about six grams. That's important not only because of the effect and the fact that it has a lower residues and all that, but it's also important because then production costs are less significant. And the situation in Germany continues to be very difficult for the entire industry. that is either dependent on raw materials or, you know, energy, significant energy. So we think, you know, products like this are sort of the answer for the future, both for the customer, but also for companies like Bayer.

speaker
Michael Christodoulou
Head of Investor Relations

Okay, and then we have a very last follow-up question from Kevin Grogan from Scrip. Kevin, over to you.

speaker
Kevin Grogan
Reporter, Scrip

Hi, Morgan. Just a quick one about ILEA. Obviously, the decrease in sales was probably bigger than expected, really. And obviously, there's a boost with a one-off payment in the UK. But you're saying you're confident that ILEA sales can be roughly in line with last year's. Where's that confidence coming from?

speaker
Bill Anderson
Chief Operating Officer

Yeah, thanks. Thanks, Kevin. So ILEA, we're seeing two things happening. One is that the uptake is very strong of the new high dose, the eight milligram dose. Patients and doctors really prefer the long dosing intervals and really that ability to maintain efficacy with fewer doses. And that's a big deal, obviously, in a treatment area where you have to give injections into the eye. So we're seeing good uptake there. We're now starting to launch the RVO indication for the high dose, and also we have a pre-filled syringe for high dose. So we're seeing good adoption of the high dose, and so that's our reason for confidence. The challenge that we see is that the launches of the 2-mig dose of biosimilars is actually having a bigger effect, not so much on our volume, but on our pricing. And so that's why the results were a little softer than we were expecting. But we believe that the combination of new indications, pre-filled syringe, and then just the general preference for the less frequent dosing means we'll have a strong run with ILEA for years to come. Thanks very much.

speaker
Michael Christodoulou
Head of Investor Relations

All right. Thank you very much, Bill. Thanks, Wolfgang. And thank you very much for your questions and also for your interest. This concludes our call for today and we all wish you a very good day. Thank you very much.

Disclaimer

This conference call transcript was computer generated and almost certianly contains errors. This transcript is provided for information purposes only.EarningsCall, LLC makes no representation about the accuracy of the aforementioned transcript, and you are cautioned not to place undue reliance on the information provided by the transcript.

-

-