11/3/2025

speaker
Operator
Conference Operator

Good day and welcome to the Bruker Corporation third quarter 2025 earnings conference call. All participants will be in a listen-only mode. Should you need assistance, please signal a conference specialist by pressing the star key followed by zero. After today's presentation, there will be an opportunity to ask questions. To ask a question, you may press star then one on a touch-tone phone. To withdraw your question, please press star and then two. Also, please limit yourself to one question and one follow-up. Please note this event is being recorded. I would now like to turn the conference over to Joe Costa, Director of Bruker Investor Relations. Please go ahead.

speaker
Joe Costa
Director of Investor Relations

Good morning. I would like to welcome everyone to Bruker Corporation's third quarter 2025 earnings conference call. My name is Joe Costa, and I am the Director of Bruker Investor Relations. Joining me on today's call are our President and CEO, Frank Laukeen, and our EVP and CFO, Gerald Herman. In addition to the earnings release we issued earlier today, during today's conference call, we will be referencing a slide presentation that can be downloaded from the Events and Presentations section of Brooker's Investor Relations website. During today's call, we will be highlighting non-GAAP financial information. Reconciliations of our non-gap-to-gap financial measures are included in our earnings release and are posted on our website at ir.bruker.com. Before we begin, I would like to reference Bruker's safe harbor statement, which is shown on slide two of the presentation. During this conference call, we will make forward-looking statements regarding future events and the financial and operational performance of the company that involve risks and uncertainties. including those related to acquisitions, geopolitical risks, tariffs, foreign currency, market demand, or supply chains. The company's actual results may differ materially from such statements. Factors that might cause such differences include, but are not limited to, those discussed in today's earnings release and in our Form 10-K for the period ending December 31, 2024, as updated by our other SEC filings, which are available on our website and on the SEC's website. Also, please note that the following information is based on current business conditions and on our outlook as of today, November 3rd, 2025. We do not intend to update our forward-looking statements based on new information, future events, or for other reasons except as may be required by law prior to the release of our fourth quarter and full year 2025 financial results expected in February 2026. You should not rely on these forward-looking statements as necessarily representing our reviews or outlook as of any date after today. We will begin today's call with Frank providing an overview of our business progress. Gerald will then cover the financials for the third quarter of 2025 in more detail and share our updated full year of 2025 financial outlook. Now, I'd like to turn the call over to Brooker's CEO, Frank Laukeen.

speaker
Frank Laukien
President and CEO

Thank you, Joe. Good morning, everyone, and thank you for joining us on today's third quarter 2025 earnings call. As forecasted, our third quarter revenues and earnings were down year over year, primarily due to weaker academic and research instruments demand in the first half of 2025. However, our Q3-25 performance was quite a bit better than expected and represents a meaningful sequential step up from our Q2 performance. In this third quarter, we were encouraged by our mid-single-digit percentage organic bookings growth. For the first time this year, we saw strength in bookings in the academic government market segment as well as improving biopharma and applied market orders. Interestingly, in Q3 of 25, we saw the stark contrast of a double-digit percentage organic revenue decline in the AccaGov markets year over year, compared to a double-digit percentage organic improvement in AccaGov bookings year over year. In fact, our AccaGov orders grew in the high teens percentage in Q3 25, has very robust order growth outside of the United States, more than offset a continued year-over-year softness in the U.S. A lot of moving pieces. Anyway, notably, our innovative spatial biology, proteomics, and multiomics solutions launched at AGBT, AACR, and ASMS earlier this year are being very well received by our biopharma and academic customers. And enhance our leadership in enabling tools for drug discovery and disease biology research in the post-genomic era. Biopharma and Applied also saw organic bookings growth in Q3, with Biopharma having the strongest organic order growth of all of our end markets, both in Q3 and year-to-date. Organic scientific instrument orders in China increased by double-digit percentage in the third quarter year-over-year, and we saw what may be green shoots of stimulus funding in China beginning to be dispersed. So this stronger Q3 25 order performance drove our scientific instrument segment book-to-bill ratio to greater than 1.0 for the first time in several quarters. While one quarter of improved orders is too early to call a trend, we are encouraged that our two divisions, most directly tied to macroeconomic factors, which happens to be Bruker Optics and AXS, also saw strong bookings in Q3 of 25. These two divisions often serve as a leading indicator within Bruker for changing macro market trends. However, due to the late timing of Q3 orders and certain customer site delays, we are reducing our organic revenue growth expectations for the fourth quarter and our guidance for the full year. This also de-risks our implied fourth quarter forecast to levels that we are very confident we can achieve. Finally, on this slide, our major cost savings initiatives announced last quarter are progressing very well towards the high end of our 100 million to 120 million cost down targets for 2026. And they are expected to deliver significant margin expansion and double digit EPS growth in 2026. All right, turning to slide four now. In Q3-25, continued softness in ACAGOV revenues led to year-over-year declines throughout the P&L. However, we noted sequential improvements in biopharma, microbiology, and diagnostic revenues, which led to both top and bottom line coming in better than our expectations in early August. Brooker's Q325 reported revenues decreased half a percent to $860.5 million, which included a currency tailwind of 2.9%. On an organic basis, revenues decreased 4.5%, which included a 5.4% organic decline in scientific instruments and 6.9% organic growth at best net of intercompany eliminations. revenue growth from acquisitions added 1.1%. Our third quarter 25 non-GAAP operating margin was 12.3%, a decrease of 260 bps year over year as lower revenue absorption, additional tariff costs and currency headwinds were only partially mitigated in Q3 by our earlier costs and pricing actions. Our third quarter 25 non-GAAP operating margin of 12.3% represented a meaningful sequential improvement over the 9.0% we reported in the second quarter. Our third quarter diluted non-GAAP EPS was 45 cents, down 25% from 60 cents in Q3 of 24, but up sequentially compared to the 32 cents we reported in the second quarter of 25. Carol will obviously discuss the drivers for margin in EPS later in more detail. Moving to slide five, our year-to-date Q3 revenue increased by 3.0% to $2.5 billion. Organic revenue declined 3.1% with a 2.9% organic decline in scientific instruments and a 5.5% organic decline at best net of intercompany eliminations. Our first nine months, 2025, non-GAAP growth and operating margin and GAAP and non-GAAP EPS performance are all summarized on slide five. So, please turn to slide six and seven, where we highlight the year-to-date third quarter performance of our three scientific instruments group and of our best segments, all on a constant currency and year-over-year basis. Year-to-date 2025, BioSpin group CR revenue, F612 million was shown, excuse me, was down mid single digits percentage. BioSpin saw growth in lab automation and services offset by a tough comparison with two gigahertz class NMR systems in Q3 24 revenue versus none in Q3 of 25. BioSpin saw weakness in ACADUB and BioPharma revenues, but improved order growth in both end markets in the third quarter of 2025. Year-to-date 2025, Cowlick Group revenue of $879 million increased in the low double-digit percentage, driven by microbiology and infection disease diagnostics. with strength in both the Maldi Biotyper and the Alitech Molecular Diagnostics franchises. Life Science Mass Spectrometry is seeing early traction for recently launched products, including the new TIMS Omni and the new TIMS Metabo, both launched at ASMS. While our molecular spectroscopy revenues remain stable, but with strong applied markets orders in Q3-25, as was mentioned earlier. Right, turn to slide seven now, please. Year-to-date 2025, brooker nano revenue of $775 million declined in the low single-digit percentage. Revenues from advanced X-ray and nano analysis tools were down year-over-year, partially offset by growth in spatial biology. Strength in biopharma year-to-date revenues was offset by weakness in agar-garb and software industrial research and semi-markets. Finally, year-to-date 2025, best revenues declined in the mid-single-digit percentage net of intercompany eliminations. The clinical MRI superconducting wire market improved in Q3 and is now flat year-to-date, while our best research instruments business has been weaker due to a very strong prior year comparison. So, moving on to slide eight, you may have seen our press release that we had some recent NIH and NSF-funded orders for advanced NMR instruments. I won't go through all of them, but here are several very unique enabling and breakthrough tools listed on this page with the respective customers that are really very important for fundamental scientific research, and very much so also for drug discovery and disease biology research. The aggregate value of these orders was disclosed previously. It's about $10 million. They're all expected to be installed and in revenue next year, not in Q4, and maybe the Bigger message here is in that last bullet on slide eight, that our scientific instrument ACADABO orders, as I mentioned earlier, we were pleased we're all up mid-teens percentage organically year over year in Q3, and this was despite lingering US weakness. There's been some improvements in the US, but primarily there's significant improvements outside of the US, Europe, Japan, and in China. Right. Another press release, if you go to slide 9, that we stressed yet recently, there are some new, if you like, applied markets. This is not food testing. This is security and defense and homeland security. And in this case, we have a very, very nice product line that's sort of growing rapidly, 30% year over year. And we were highlighting some recent orders from explosive trace detectors that you will find at a lot of European airports, an increasing number of those. but also in South Korea and the Middle East. They have particularly performance and usability advantages. This, by the way, isn't just an instrument sale. This has been five or seven years of consumables and service sales, so it's a nice, steady business, and we have been gaining market share and are pleased with those orders. And because of tensions and rearming in Europe, we also got some significant defense detection orders from a Central European Ministry of Defense. This was not for Ukraine, but others are worried as well. And obviously, this is a smaller part of Bruker that, if you like, is part of applied markets. That's growing very nicely. We thought we'd highlight that for you because, obviously, Akagab was weaker this year. So, to wrap up, our third quarter P&L was still impacted by the various headwinds we've seen across the industry earlier this year. However, the results came in ahead of our expectations. Our improved bookings in Q3-25 and scientific instruments book-to-bill ratio above 1.0 make us optimistic that we may be past the trough in demand. We look to build on this performance in Q4, and we are increasingly confident in a fiscal year 26 partial recovery. We expect significant improvements in our organic revenue performance compared to our meaningful decline, organic decline in 25. Importantly, we are taking up to $120 million in cost out of our business in fiscal year 26 in order to drive significant margin expansion and strong double-digit EPS growth. So in perspective, our Transform Project Accelerate 2.0 portfolio is fundamentally very strong. In post-genomic drug discovery and disease biology research, leveraging both proteomics and multiomics, as well as spatial biology, in innovative diagnostic solutions for microbiology, molecular diagnostics, and now also therapeutic drug monitoring, And finally, emerging, really an emerging $100 million area for us is now the fast growth area of automated, digitized, or digital labs ready for AI or perhaps even driven by AI, the automated AI labs, if you like. These are four major profitable growth opportunities today. and they are complemented by our healthy diversification in industrial research, UC market, semiconductor metrology, and, as you've seen, applied and security markets. Combining this outstanding portfolio with operational excellence and strong execution, I am confident that by 2027, we can outgrow our markets again by 200 to 300 dips per year on average and continue our rapid margin expansion and double-digit EPS growth. after overcoming the multiple Akagov demand, new tariffs, and strong currency headwinds in 2025, with a partial recovery in 2026. So with all of that, let me turn the call over now to our CFO, Gerald Herman, who will review things in more detail. Gerald.

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

Thank you, Frank, and thank you, everyone, for joining us today. Pleased to provide some more detail on Bruker's third quarter and year-to-date 2025 financial performance. starting on slide 11. In the third quarter of 2025, our results came in above our expectations on both the top and bottom lines. In the third quarter of 2025, brokers' reported revenue decreased 0.5% to $860.5 million, which reflects an organic revenue decrease of 4.5% year-over-year. Acquisitions contributed 1.1% to our top line, while foreign exchange was a 2.9% tailwind. Geographically, and on a year-over-year organic basis, in the third quarter of 25, America's revenue declined in the low single-digit percentage. European revenue was roughly flat, while Asia-Pacific revenue declined in the mid-single-digit percentage, including flat performance in China. For our EMEA region, revenue declined by over 20%. Scientific Instruments Organic Revenue Group Segment declined 5.4% in the third quarter of 25, as mid-single-digit organic growth in CALID was more than offset by a double-digit organic decline in BioSpin and a high single-digit organic decline in Bruker Nano. BSI systems revenue declined roughly 10%, while BSI aftermarket revenue increased mid-single-digit percentage. organically year-over-year. As Frank mentioned earlier, our order bookings performance in the BSI segment was up organically in the mid-single-digit percentage year-over-year, and our BSI book-to-bill ratio for the third quarter was above 1.0. Non-GAAP gross margin decreased 110 basis points to 50.1%. Q3 2025, non-GAAP operating margin was 12.3%, impacted by tariffs, foreign exchange, and the headwind from the prior year comparison of two gigahertz class NMRs in our third quarter 24 revenue. On a non-GAAP basis, Q3 25 diluted EPS was 45 cents, down 25% from 60 cents we posted in the third quarter 24, but improved sequentially and well ahead of our expectations. Our EPS in the third quarter 25 includes A one-cent dilution from the mandatory convertible preferred offering we completed in September and benefited from a lower nine-gap effective tax rate of 24.4%. On a gap basis, we reported diluted loss per share of 41 cents, reflecting non-cash goodwill and intangibles impairment charges of $119.4 million and restructuring charges in the third quarter of $34.5 million. Non-GAAP weighted average diluted shares outstanding in the third quarter of 2025 were 152 million flat compared to the third quarter of 2024. Slide 12 shows Brooker's performance on a year-to-date basis for 2025, which has similar drivers to those in the third quarter. Turning now to slide 13, in the first nine months of 2025, we had operating cash outflow of $95.7 million driven by lower profitability, timing of tax and key vendor payments, and restructuring expenses. We expect to see improved cash flow in the fourth quarter, our largest and most profitable quarter of the year, and always our strongest cash flow quarter. Turning now to slide 15, we are updating our full year 2025 forecast and outlook to reflect Q3 results order timing, and the impact of our September mandatory convertible preferred offering. Our outlook for the full year of 2025 now assumes revenue in a range of $3.41 to $3.44 billion, reflecting an organic revenue decline of 4% to 5%. Late order bookings in the third quarter, as well as certain customer site readiness issues, are expected to push a portion of revenue we previously expected in the fourth quarter into fiscal year 2026. The full year 25 revenue growth contribution from acquisitions is expected to be approximately 3.5%, and we expect a foreign currency tailwind of about 2.5%. This leads to updated reported revenue growth guidance of 1 to 2%. For operating margins in 2025, we now expect approximately 250 basis point decline in operating margins year over year. This consists of headwinds of 60 basis points from M&A, 60 basis points from tariffs, 65 basis points from foreign exchange, as well as a 65 basis point decline in organic operating margin. On the bottom line are updated Full-year 2025 guide now reflects non-GAAP EPS in a range of 185 to 190. This includes a $0.07 dilution from our mandatory convertible preferred offering we completed in September. For your modeling, we expect the MCP offering to have a roughly $0.20 dilutive impact on our fiscal year 2026 EPS. Despite this dilution, we continue to expect double-digit non-GAAP EPS growth in fiscal year 26 due to the significant cost savings initiatives we're implementing this year. Other guidance assumptions are listed on the slide. Our full year 2025 ranges have been updated for foreign currency rates as of September 30th, 2025. With respect to the fourth quarter of 2025, we still expect relatively soft organic revenue performance with a mid to high single-digit percentage decline year-over-year due to lingering effects of weaker orders earlier in the year. We expect on-gap EPS for the fourth quarter to show significant sequential improvement but still be down meaningfully year-over-year, as implied by our guidance. To wrap up, First half 2025 market headwinds adversely impacted our financial performance in the full year of 2025. However, we're encouraged by our solid order performance in the third quarter of 2025 and expect to drive improved P&L performance in full year 26 and beyond. With our cost savings plans well on track, we're fully committed to significant margin expansion and double-digit EPS growth in fiscal year 26. With that, I'd like to turn the call back over to Joe. Thanks very much.

speaker
Joe Costa
Director of Investor Relations

Thanks, Gerald. We will now begin the Q&A portion of the call. As a reminder, to allow everyone time for questions, we ask that you limit yourself to one question and one follow-up. Operator?

speaker
Operator
Conference Operator

We will now begin the question and answer session. To ask a question, you may press star then 1 on your touchtone phone. If you're using a speakerphone, pick up the handset before pressing the keys. If at any time your question has been addressed and you would like to withdraw your question, please press star and then two. Our first question comes from Panit Sada with Lear Inc. Partners. Please go ahead.

speaker
Panit Sada
Analyst, Lear Inc. Partners

Yeah. Hi, Frank. Thanks for taking my questions here. First one on the book to bill, good to see more than one and congrats on the quarter. Just given the older momentum you're seeing here, but Just wondering how has that trended in the fourth quarter? Are you continuing to see the mid-teens organic order growth here? And maybe could you elaborate a bit, just a number of moving parts here. How is the international momentum continued? Is it more Akego versus Pharma? And maybe tell us a bit more on the academic side of the U.S. Are you starting to see some you know, some recovery there, given the points you mentioned, DNP, and a couple other points you mentioned in the slide.

speaker
Frank Laukien
President and CEO

Yes, thank you very much, Puneet. So, we really don't have Q4 data yet. It's too early. So, I just can't comment on Q4. There's no meaningful data available yet. Moving parts, ACCA, GOV, the strength in ACCA-Gov orders was primarily outside of the United States, but the United States were less weak. All right, less soft. Is that a word? Anyway, so QQ3 was better in the United States for ACCA-Gov orders than Q2, and we saw some orders come through. I gave you some NMR examples, but, of course, it was broader than that. It also included TIMSTOP and microscopes and other stuff. Hard to say what's the trend in the U.S. because clearly in the U.S. there was a little bit of catch-up in Q3 compared to Q2 and maybe even Q1 in ACAGAV orders in Europe and Japan and a little bit in China also. That's why there might be green shoots were quite encouraging, and that's why our ACAGAV orders Year over year, we're up considerably in Q3. Don't think that we're now in a high teens growth trend all of a sudden. That's just a quarter, and Q3-24 was not the strongest. But anyway, it was very encouraging. And we hope that we'll continue in Q4, but I wouldn't. And, yeah, the activity and opportunities are great and are encouraging. but I wouldn't read anything into that yet. Just early to comment on Q4. We do need Q4 to then give more meaningful growth and margin numbers for 2026. We're not going to do that today. We're not able to do that today until we really see how Q4 comes in, particularly the orders, obviously. To the other moving pieces, Puneet, yes, biopharma has been reasonable or cave, not grave, but okay in the first half of the year, much better in the third half of the year in terms of orders, a particular strength there in the U.S., but also outside of the U.S., biopharma particularly in the U.S. And the applied market strength, which is a good sign of macroeconomic trends, that had a pretty broad international distribution. I don't know that I would highlight any geography there. So that may add some color to the, admittedly, multiple moving pieces. And the effect that Bruker, that prior order weakness, now shows up in the P&L, whereas, you know, the new order improvements and encouragement and maybe this momentum, if Q4 goes well, you know, it's more likely to show up all in 2026. Hope that helps.

speaker
Panit Sada
Analyst, Lear Inc. Partners

Got it. That's very helpful. And anything on the ultra-high frequency gigahertz NMRs, how are you thinking about those? Obviously, the tougher comp in the third quarter, but as you go into 26, how is the momentum there? I know we've been waiting for U.S. to acquire more of those instruments.

speaker
Frank Laukien
President and CEO

Thank you. Yeah, the US is the enigma there. But you know, obviously, there's also other geographies. And I still can't call the US trends. Obviously, nothing has come through so far. So we'll see. We're expecting at least one order for the gigahertz class in Q4, not in the US. And there's a number of cases. growing around the world and including in the US. But I, you know, today's too early to do that. So when we give guidance for 26 in, you know, presumably in early February of 26, we can also comment on, you know, what has come in or where we have clear line of sight for ultra high field for the gigahertz class. So yes, nothing in revenue in Q3. We expect hopefully one order in Q4. Sometimes these things get delayed by a quarter. Anyway, it's just not such a big part of our business anymore. I know they're easier to count. And indeed, in Q3, a lot of our organic decline had to do with these two gigahertz class systems in Q3 24 revenue, which accounted for more than 25 million of our revenue and comes with nice operating profits and margins. So it did have an effect on Q3. And anyway, that's the color I can give you. More to come when we give guidance in early February.

speaker
Panit Sada
Analyst, Lear Inc. Partners

Got it.

speaker
Frank Laukien
President and CEO

Thank you.

speaker
Operator
Conference Operator

And the next question comes from Michael Ryskin with Bank of America. Please go ahead. Michael, your line may be on mute.

speaker
Michael Ryskin
Analyst, Bank of America

Hi. This is Mike on for Mike. Could you give us the impact of the government shutdown that you're seeing in 4Q, and is that baked into the updated outlook? Thank you.

speaker
Frank Laukien
President and CEO

Well, that's a good question, and it's not formally baked into our outlook. So far, we have assumed that the effect will be relatively minor but you know indeed if uh if this were to continue for a full second month or so then this may delay some new grants some orders it could also delay some installations um so far we haven't become aware of anything that gets we said we think that our q4 guidance is now appropriately conservative to absorb some of that and maybe what we've seen so far but know if there was a further multi-week or multi-month shutdown that could have additional impacts that are not presently in our guidance.

speaker
Michael Ryskin
Analyst, Bank of America

Understood. Thank you. And then I know that you're not formally guiding on 2026 today, but, you know, you called out meaningful improvement versus the minus 45% organic in 25.

speaker
Frank Laukien
President and CEO

um can is it fair to assume that you can grow revenues in 2026 or um are we looking at side of year over year thank you we're not making that assumption yet it's a fair question of course um we really do want to see our q425 bookings uh in order then to give you know hopefully reliable guidance in february of 26. um So yes, I mean, this year 25, we're coming down organically quite a bit, right? We undoubtedly can do much better than that next year, but we're not presently, I don't want to state any assumptions because then you will take them as guidance and they're not, but we just want to make sure that with a significant cost cutting that we're doing, even without growth, which isn't our assumption, Even without growth, we can expand our operating profit margins very significantly, say 250 to 300 bps or something like that. And yes, we expect, we continue to expect double-digit EPS growth even after absorbing the roughly 20-cent dilution that Gerald mentioned during his prepared remarks for the additional dilution from the mandatory converts that we did in September. So we still expect to do double-digit non-GAAP EPS growth next year. And that's without, that's simply for mathematically, that's simply, we're not, this is without growth. Without growth is not our preliminary guidance. Period. But that's what we're looking at right now. We can have preliminary guidance for us right now on growth. It does not make sense until we've seen our Q4 orders for grouper. That's going to be very important for next year.

speaker
Michael Ryskin
Analyst, Bank of America

Understood. Thank you for the color.

speaker
Frank Laukien
President and CEO

Thank you.

speaker
Operator
Conference Operator

And the next question comes from Taisha Peterson with Jefferies. Please go ahead.

speaker
Taisha Peterson
Analyst, Jefferies

Hey, thanks. Frank, I want to pick up on that margin point. So it sounds like you are committing to the 300 basis points of margin expansion, even if it's top line flat, I guess. And, you know, given that you're running at the high end of the $100 to $120 million cost savings target, you know, in the near term, should we interpret, you know, the upper end of savings as simply kind of increasing confidence in hitting that margin target next year? Or could you think you could potentially do better?

speaker
Frank Laukien
President and CEO

Okay, so nice question, Tycho. I wasn't confirming a number. I know you've mentioned one. I'm not saying take that number out of your model, but I'm not confirming it either. We are, I think the second part of your question, I think it's fair to say, we hope to, you know, have increased confidence in in getting to very significant margin expansion and double-digit EPS growth all in, including the MCP. And that's exactly why we're driving towards the high end of our cost-cutting target. So you're spot on with that one.

speaker
Taisha Peterson
Analyst, Jefferies

Okay. And then just probing a little bit on your assumptions. You know, we're not talking numbers for 26, but just A&G, the outlook there, assuming flattish NIH budget. I mean, just talk a little bit about some of the give and takes around, you know, multi-year grants. I assume you're not expecting any budget flush here in the near term, but then as we think about next year, do you think, you know, ANG orders, you know, will grow? And then can you flesh out your comments on China stimulus? You know, how material was that, and how do you think about that for next year?

speaker
Frank Laukien
President and CEO

Yeah, these are all very important questions, right? So there was a little bit of a budget flush for the fiscal year 25, and orders, sorry, and funding, coming out of NIH, you all report that very well, did improve in the third quarter and particularly in September. I'm aware of a cancer center that had fantastic NIH funding and cash coming in the door to where they even were flat or higher than the previous year. So there was a mini-budget flush. It went into a lot of multi-year grants. It went into things that they could fund readily. It went into a few instruments, too. You know, we sold some NMRs and some Tim Topp and some other stuff. It wasn't very strong yet, which is why the strength in academic bookings for us in Q3 came from outside the U.S., But the U.S. did improve a little bit sequentially. It just wasn't a growth driver yet year over year. So that was that. NIH budget for 26, an NSF budget while we're at it. We are not necessarily assuming that it's flat. We'd be delighted that it's flat. You know, if we have to take 10% or 15% down, I think that'll work for us too. I just want to be... It's hard to predict these things, these things, so we're not necessarily baking in an NIH budget flat. Again, delighted if it happens, but we can also work with it being down 10 or 15%. As you know, it's then actually more important whether the stuff actually gets dispersed regularly or gets held up for the majority of the year. But we are, along with Q4 bookings, we're also looking forward to clarity on NIH and NSF and DOE budgets for research for fiscal year 26. Hopefully that all comes in in calendar Q4 to give us more visibility. China, yeah, some green shoots, yeah. So there were less than 10 million in clearly – well, in orders anyway, but in clearly seemingly – stimulus-related orders where a customer said, yeah, this is stimulus money being released. So less than 10 million, not, and, you know, again, I think that's a green shoot. And we'll need to, again, see how that continues in Q4. But I think in Q2 there was none of that, so it's a little bit better, right? So China contributed, but Japan and, quite honestly, Europe were really strong in ACAGAV orders in Q3. So that's the color of the world, yeah.

speaker
Taisha Peterson
Analyst, Jefferies

Okay, thanks. And then lastly, you just mentioned an order pushout. Can you quantify how large that was, the one you mentioned in your prepared comments?

speaker
Frank Laukien
President and CEO

You mean revenue pushout? Yeah, there's a few sites that, you know, have that. one delivery in Q1 rather than in Q4. So that also added to some of the more conservative guidance that we now have for the full year, but really implied for Q4, because that's all that's left. Okay, thanks. And I think I mentioned a lot, it is true that, I mean, it's always true that we get more than half the orders in a quarter in the third month of every quarter, but yes, a lot of the orders and in the order improvement really became clear in September. So, you know, if all of these orders had come in in July, maybe some of them would have made it into Q4. But now, I mean, there's some small stuff that will go into Q4, and all this does. But most of the larger orders go into next year. Most of the larger orders that came in in September will be revenue in next year, I should be precise.

speaker
Taisha Peterson
Analyst, Jefferies

Thank you. Thanks.

speaker
Operator
Conference Operator

The next question comes from Luke Sergot with Barclays. Please go ahead.

speaker
Luke Sergot
Analyst, Barclays

Great. Thanks for the questions. I just want to talk on China. I know you're coming in flat here. Things kind of improve sequentially. Just talk about what you're seeing there more broadly. Pull forward. You talked a little bit about the stimulus, you know, the murder's row of key questions. But, you know, how are you guys thinking about 4Q and the exit rate? And ultimately, are we kind of seeing some type of stabilization here, or is this just kind of like a one-off?

speaker
Frank Laukien
President and CEO

Well, good questions. I wouldn't read too much into, starting backwards, Luke, I wouldn't read too much into the Q4-25 exit rate. That's just, you know, Q3 and Q4 are relatively weak on the P&L. It's pretty much the result of weak orders and, yes, and some, you know, current new currency and tariff challenges early in the year. We can work our way through those and offset them and more than offset them by next year, but only partially this year. So I wouldn't, I would hesitate to take any given quarter this year as modeling something for next year. On China, yeah, China was a little bit better, right, sequentially. not only in academic, not only some of the, you know, less than 10 million, I think it was close to the six or something like that, in stimulus, green shoots. China felt a little better in Q3, perhaps all around, than in Q2 when they were probably staring down a trade war barrel and maybe now, maybe now there's, maybe that gets That seems to have, even before the meeting that just happened recently, maybe the whole world's getting a little bit more optimistic that, well, we know the new tariffs set up and there are not likely to be major trade wars. But hard to say, right? So China was a little better in Q3 than in Q2.

speaker
Luke Sergot
Analyst, Barclays

All right, thanks. And then I turn to the spatial and the demand that you guys are seeing there. Can you talk a little bit about the – Cadence for the instruments versus the consumables. And then, you know, the push here and ability to use your existing scale as this kind of hits the core to push further with academic government customers or deeper into pharma.

speaker
Frank Laukien
President and CEO

Yeah, good question. Yeah, spatial biology was all right. Slightly better orders or somewhat better orders in Q3, including international, I believe, as well. That's both. consumables and instruments uh remember some of the new workflows like the whole transcriptome on the cosmics of course also will run on existing systems they may need some upgrades but you don't always need a new system for that but i think there was also strength in cosmics and cellscape orders paintscape is still very new so a lot of that is sort of uh will will take a little while and and have a number of labs that are going to have placements of the pain scape, do this new spatial genomics and look at, you know, dysfunction in cancer and infectious disease. Before that turns into papers, before that turns into revenue sets, that's super interesting, but it's not going to be a big contributor yet, whereas Cosmix and CellScape are doing well, also including some of the consumables. So, yes, spatial biology is doing better. Of course, we could use more U.S. academic funding. It was quite dependent. Well, two-thirds of that is academic government, and one-third is biopharma. And so that strengthening in biopharma also is good for spatial biology. And as you know, that so far in the U.S., that's stronger than the ECHA-Gov growth. Yeah. Great.

speaker
Luke Sergot
Analyst, Barclays

Thanks.

speaker
Operator
Conference Operator

And the next question comes from Nubu Nambi with Guggenheim. Please go ahead.

speaker
Nubu Nambi
Analyst, Guggenheim

Hey, thank you for taking my question. Frank, some of the niches in markets in 2026, like diagnostics and maybe semis, what do those look like next year? Can any tech be a low double-digit grower in your mind?

speaker
Frank Laukien
President and CEO

Yeah, I mean, diagnostics is very important for us, right? It's well above $500 million. They both are – they've done well in 25, both in clinical microbiology and the molecular diagnostics that are both in that infectious disease division. Multibiotyper, good growth, very good growth in consumables and software and so on. Now in that business, I think it's 60% aftermarket, which is, you know, service consumables, but also database subscriptions. So very healthy there. The diagnostics business, the Elitech business primarily is a delight this year. It's growing nicely. It's expanding. It's this year 25, so it's growing its margins. It's growing, which is nice this year. It's like she has I don't know the exact growth rate. It's growing somewhere in the single digits, maybe even high single digits, which is lovely. Its placements have really outperformed significantly. I know you can't take placements to the bank, but next year you will be. So they had a lot of placements of their InGenius and BGenius stations. The commercial synergies with Brooker are really working, and they're getting into countries and into labs they previously couldn't get. So I think their placements are something like 20% or more ahead of their business plan, which isn't revenue this year. That's when these systems are placement underage and rentals, then it takes six months until you really have the revenue ramp. But, you know, hopefully then you have five to seven years of really solid revenue and consumables pull through. So that's going really well. Semi is – You have to look at it in the annual basis. I think we had two, this year we'll have two quarters of fantastic orders and two quarters of not so fantastic orders. Over the year, it's all right. I think it's flattish this year. I don't think there's anything structural there. And revenue-wise, it's been a little weaker, and we expect that to improve next year. So SEMI really has to look at it on an annual level. And it's a very nice margin contributor. Semi now is approaching or is around $300 million in annual revenue. So it's also pretty meaningful for us. And it's very, along with the diagnostics business, has some of the best incremental margins. So those are very core to us. These are not niches for us, even though we love the post-genomic era. Both of those are just really important core businesses.

speaker
Nubu Nambi
Analyst, Guggenheim

Thank you for that, Frank. Just a follow-up. Can you unpack where you saw orders incrementally positive from a product perspective? Is it the lower price equipment? And then how have consumables been impacted? Any color you could share there.

speaker
Frank Laukien
President and CEO

So it's prime for diagnostics, for molecular diagnostics and the Alatec. Remember, they're primarily active in Europe, in France, selected countries uh in in asia like not in china for instance um in in parts of africa parts of latin america and the strength there has been particularly in europe the placement strengths that i mentioned can you repeat the question super i'm sorry what was i thought you were referring to diagnostics but

speaker
Nubu Nambi
Analyst, Guggenheim

yes diagnostics yeah i'm sorry backing up in general the order strength that you saw this quarter where did you see uh the strength coming from from a product perspective either diagnostics or outside of diagnostics and i think this is gerald i'd say that the order's strength in the third quarter was coming from larger um asp based

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

instruments. We did have some volume, particularly coming out of our optics and AXS businesses, which tend to have lower ASPs, but I'd say that the bulk of the performance in the orders was particularly, you know, coming out of the European markets as well, just to clarify that. And we saw considerable strength in the European markets, both in the AGCOV side.

speaker
Frank Laukien
President and CEO

So I think I can answer it now. Sorry, it took me a second. The strength in orders in Q3 of 25 had very little to do with diagnostics. Diagnostics was just coming along and it's fine, but the more discrete items were strength in ACCA-GAV outside of the U.S., biopharma, and applied. That's right. And so none of those include diagnostics.

speaker
Nubu Nambi
Analyst, Guggenheim

Thank you for that.

speaker
Operator
Conference Operator

And the next question comes from Casey Woodring with JP Morgan. Please go ahead.

speaker
Casey Woodring
Analyst, JPMorgan

Great. Thank you for taking my questions. On orders, you know, historically, orders improve sequentially in 4Q in your business, but you've talked here today about some catch-up in academic and government in 3Q. So, can you just maybe walk through what the range of outcomes looks like in 4Q from an order exit rate perspective? You know, how safe is it to assume orders step up sequentially, or are there scenarios wherein orders could be flat down? in 4Q, and I have a follow-up.

speaker
Frank Laukien
President and CEO

Thanks. Okay, so in ECHAgov, where we observed a little bit of catch-up was in the U.S. I don't think that, you know, there wasn't any holdback. Well, actually, in the U.S. and in China, a little bit. In the rest of the world, I think they'd catch up. I'm not aware of that. But China and the U.S. and AkaGov have been holding back. And that's why Q2 orders, for instance, in both of those geographies were weak. So to your second part of your question, Q4 is always strong. So the question for Q4 will not be, will it be up sequentially over Q3? That's pretty much a given. But whether, you know, what the trend will be year over year compared to Q4 of last year.

speaker
Casey Woodring
Analyst, JPMorgan

Got it. I hope that helps. And then, yeah, no, that definitely helps. And then my second one, just quickly on backlog, I think last quarter you noted you had six and a half months, and you talked about that going down to five months in a normalized environment. Maybe just walk through kind of how you're seeing that play out over the course of 26. Thank you.

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

Well, what I can comment on is that, you know, we currently have about seven months of backlog through the third quarter of 2025, which is actually up now from the six and a half months we quoted at the end of the second quarter. I mean, I guess, to a large extent, it really depends on our 26th performance is really going to depend on how it looks like for the fourth quarter in terms of revenue performance. Based on our guide, it looks like we will still carry considerable backlog into the 2026 period. Right. All right.

speaker
Casey Woodring
Analyst, JPMorgan

Great. Thank you. You're welcome. Thank you.

speaker
Operator
Conference Operator

And the next question comes from Brandon Collard with Wells Fargo. Please go ahead.

speaker
Brandon Collard
Analyst, Wells Fargo

Hey, Gerald, thanks for taking the questions. Just a couple of housekeeping items. You gave us an updated interest expense number for the year. What's the run rate for the fourth quarter? And is that a good figure to assume for 26? And is the impact of the share count from the MCP offering about 13 million shares?

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

Thanks. Yeah, to answer your last question first, the answer is yes, roughly. And then the first part, you know, we'll go through. Brandon, a little more modeling on the interest because it gets a little complicated, partly because we – you may know we had some gains, some foreign exchange gains that get covered in that line as well. So somewhere in that range that you're quoting on interest is correct, but we'll talk more about that in our modeling discussions.

speaker
Brandon

Okay.

speaker
Operator
Conference Operator

And the next question comes from Josh Waldman with Cleveland Research. Please go ahead.

speaker
Josh Waldman
Analyst, Cleveland Research

Thank you for you. First, I wondered if you could talk a bit more about what you're seeing in Europe. Was it primarily AccuGov accounts that improved there, or did you also see pharma-applied accounts improve as well? And then, I guess at this point, what's your confidence level on the sustainability and stronger orders? I mean, were there any one-off funding programs or anything like that that released in the third quarter that, you know, leave you, I guess, nervous about the durability of stronger orders there?

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

Yeah, I guess I'd say, generally speaking, Europe was stronger. We did see strength in both PACA, GOV, as well as applied in biopharma. So, those are good signs, and I don't think there were specific one-offs related to those trends. So, I think we're more confident, but I would say we need to see, as Frank has repeated a couple of times here, we need to see the fourth quarter order performance in order to confirm that specifically. But all of those markets, in particular, on the AkaGov side, European, were not being driven by one-off improvements or orders.

speaker
Josh Waldman
Analyst, Cleveland Research

Got it. Okay. And then a follow-up. I wondered if you could provide more color on what you're seeing out of pharma. I mean, it sounds like you saw sequential improvement in bookings. I forget if you commented what orders look like year over year. And does it seem like accounts are trying to push orders through by year end, or does this seem like maybe a change in how they're viewing medium-term investment in research tools?

speaker
Frank Laukien
President and CEO

Good questions. Josh, this is Frank. I'm not aware of any particular drives to get orders in placed in before the end of the calendar year. So I would take this as biopharma having invested less now for, you know, so there was a kind of a COVID or immediate post-COVID boom. Well, then there was a hangover, right? And then some concerns about most favorite nations' pricing and how much capex did they need to move things in production to the U.S., and many of them are now committed to do that. You know, it doesn't happen overnight. So maybe that has cleared the decks a little bit to where they are investing in tools that will, you know, make drug discovery more efficient and give them better insights. And those tools, that's exactly what we provide you. Yes, you need sequencers, but you need a hell of a lot more than that to really have deeper disease biology and then drug discovery. drug target, drug mechanism of action insight, so that hopefully the still very poor yield and enormous expense and length of bringing a successful drug to market will improve. And that requires, they're the biggest integrated fans of this hypothesis or thesis or fact, I would say, that we, you know, that we are in the post-genomic era and we need to understand The disease biology and the drug mechanism is a lot better to get less attrition and more yield and better drug discovery. So they completely agree with that. They may not use the same terminology, but that's how they're investing.

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

And I would just add that the third quarter performance on revenue was good, okay, and the order performance from biopharma across the globe was strong in the third quarter from an order perspective.

speaker
Operator
Conference Operator

Thanks, guys. And the next question comes from Doug Shank with Wook Research. Please go ahead.

speaker
Doug Shank
Analyst, Wook Research

Hey, good morning, guys. Thanks for fitting me in. Carol, how do we balance, you know, what you've talked about in terms of on the cost savings initiatives? And, you know, like you sound as good as ever on those. you've exhibited some confidence about, you know, what you can do in 2026 from a margin expansion standpoint, you know, seemingly in any growth environment. I mean, at one point, I think last quarter, you talked about getting 300 basis points of margin expansion next year, even in a flat growth environment. On the other hand, you know, I think you increased your assumption for organic operating margin headwinds by 45 basis points for the year, which is pretty material with one quarter to go. So I'm just trying to figure out, like, how do we balance these things? And is there some risk that the benefits that you expect to occur over time are going to take a little bit longer to show up in the P&L just because of maybe the environment we're in and the fact that I think a lot of these changes that you're making are being done outside the U.S. where regulations can work against you. Again, I'm just trying to think about this as we try to set you guys up to succeed with realistic targets for 2026. Thank you.

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

Yeah, sure. Nice to hear from you, Doug. So here's what I'd say. First, our Cost saving initiatives will be and we expect them to be at the high end of the range we quoted this 100 to 120 million for fiscal year 2026. And we're fully committed to that. And actually, we're well on track with that 95% of the actions that needed to be taken to realize that are already underway, or have been fully implemented. So very confident with respect to that. And I think, you know, more generally, our expectation around margin expansion of closer to 300 is where we are even under relatively weaker revenue conditions for 26. that's the position we've taken and i think we're holding to that i think the issue for us as you already know i think doug is you know some of these um activities around cost savings do take a bit of time just because we have to go through a process particularly in europe and a lot of our cost saving actions are driven around europe because of our footprint So there's going to be a slight likely delay in some of this as we would have been seeing more of it hitting in the second quarter of 2026 as opposed to in the first. But that doesn't take us off the target.

speaker
Frank Laukien
President and CEO

And let me also, I mean, so we did get Europe, there are other economic problems and layoffs by other companies. So we got very good cooperation, for instance, in Germany and France, which can be difficult from our workers' councils and comité d'entreprise. They've agreed, they've approved that what we're doing is reasonable and protects the core and all of that. So good cooperation. When Gerald said that Q1 will have So the $120 million for the year, we're very committed to that. And Q1 will have, I don't know, 90% or 95% of the run rate cost savings implemented. A few things, just the way they're timed, will come in in Q2. But it's not going to be a big modeling difference, Doug or anybody else. But, yes, that's how it flows. And the $120 million is not some sort of a Q4 run rate. That's for the full year. Exactly.

speaker
Gerald Herman
Executive Vice President and Chief Financial Officer

And just to your earlier part of your question, I mean, we did have, with perspective of fourth quarter of 25, we do have some mixed challenges in the fourth quarter for 25 that we didn't see in the previous year as well. So I think you're going to see some, you did see a change in the overall guide from an organic operating margin impact with respect to the fourth quarter. So that's the explanation for that, Doug.

speaker
Casey Woodring
Analyst, JPMorgan

Okay. I'll leave it there. Thank you, guys.

speaker
Brandon Collard
Analyst, Wells Fargo

Thank you.

speaker
Operator
Conference Operator

This concludes our question and answer session. I would like to turn the conference back over to Joe Koska for any closing remarks.

speaker
Joe Costa
Director of Investor Relations

Thank you for joining us today. Brooker's leadership team looks forward to meeting with you at an event or speaking with you directly during the fourth quarter. Feel free to reach out to me to arrange any follow-up. Have a good day.

speaker
Operator
Conference Operator

The conference is now concluded. Thank you for attending today's presentation. You may now disconnect.

Disclaimer

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