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Evotec SE

Q22026

7/14/2026

speaker
Moritz
Cross-call Operator

Welcome to the Evotech preliminary second quarter and first half 2026 results and update full year 2026 Outlook. I'm Moritz, your cross-call operator. I would like to remind you that all participants will be in the listen-only mode and the conference is being recorded. The presentation will be followed by a question and answer session. You can register for questions at any time by pressing star and one on your telephones. for operator assistance, please press star and zero. The conference must not be recorded for publication or broadcast. At this time, it's a pleasure to hand over to Sarah Fakih, head of global communications and investor relations. Please go ahead.

speaker
Sarah Fakih
Head of Global Communications and Investor Relations

Thank you, Moritz. Good morning, good afternoon, and welcome to today's webcast and conference call. My name is Sarah Fakih, and I'm the head of global communications and investor relations at Evotech. Please allow me to introduce today's speakers. Joining me on the call are Christian Wojczewski, Chief Executive Officer of Evotec, and Claire Hinshelwood, our Chief Financial Officer. Please note that this call is being webcast live and will be archived in the events calendar on our website. Before we begin, a few forward-looking statements. The discussion and responses to your questions on this call reflect management's views as of today, Tuesday, July 14th, 2026. During this call, we will make statements and provide responses that state our intentions, beliefs, expectations or projections regarding the future. These statements constitute forward-looking statements within the meaning of applicable securities laws. They are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied. Evotec disclaims any intention or obligation to update or revise any forward-looking statements to reflect subsequent events or circumstances. For further information regarding these risks and uncertainties, please refer to our public filings and disclosures. With this, let me hand over the call to Christian.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Thank you, Sarah. Good morning and good afternoon to everyone. Thank you for joining today's call. Following our announcement last night, we are providing today an update based on preliminary unaudited financial results for the second quarter and first half of 2026, as well as an updated outlook for the full year. As a reminder, publication of our full financial results is scheduled for August 13. During our full year 2025 results presentation in April, We guided for a challenging first half of 2026. This outlook primarily reflected our anticipated continuation of the softness in the early drug discovery market seen in 2025, as well as the effect of the non-recurrence of the $25 million in those licensing payment in the first quarter of the previous year. Our preliminary second quarter results extend the trends we saw in the first quarter. Group revenues in the first half of 26 are expected to amount to 300.1 million euros, while adjusted Group EBITDA is expected to land at minus 42.7 million euros compared with the first half of 2025. Our expectation in April for a stronger second half of 2026 was based on two assumptions. A gradual recovery in market activity and increasing contributions from strategic partnership activities. Based on our current visibility for the second half, we're now revising the assumptions on strategic partnerships and as a result, updating our four-year guidance. The key drivers behind this revision are summarized on the right-hand side of the slide and can be grouped into three categories. The first category relates to phasing and milestone related revenues from existing strategic partnerships across both segments. These account for approximately 40% of the revenue difference between our original and updated outlook. Importantly, these revenues are delayed, not lost, and I expect it to be recognized in 27 rather than 26. The second category relates to potential new strategic partnerships in our DNPD segment. We now expect lower than anticipated revenue contributions in the second half of 26 as a result of longer timelines for reaching and finalizing new agreements. This category accounts for approximately 45% of the revenue difference. Importantly, our underlying partnership pipeline remains healthy and active with multiple opportunities at various stages of engagement, including advanced discussions with potential big pharma partners. While we are highly confident about establishing new partnerships, Any agreements reached this year are unlikely to contribute meaningfully to revenue in 26. In addition, the timing and structures of individual deals may influence the balance of upfront cash payments, revenue generating activities, and milestone contributions in 27 and beyond. The third category relates to sales to revenue conversion. Although commercial activity and customer engagement have clearly improved, conversion into revenue has occurred more slowly than anticipated. While a small portion of revenue conversion is expected to shift into 27, approximately 15% of the revenue difference is attributable to lower than expected revenue conversion in 26 relative to our previous guidance. This portion relates to an acceleration objective we had set for ourselves, but which has not materialized to the extent originally assumed. As a result of these factors, we're updating our full year 26 guidance and Claire will speak about this in more detail later. While this revision is clearly disappointing, it is important to emphasize that It is primarily driven by the timing of partnership planning activities and ongoing partnership milestone revenues, rather than any fundamental change in these opportunities. The number and value of partnerships we are pursuing has not changed substantially. However, the conversion of these opportunities will take longer than expected. At the same time, leading commercial indicators in the first half of 26 document encouraging increased activity across our base DMPD business, including strengthening customer engagement and growing net sales. We're confirming the positive momentum highlighted over recent quarters and expect those to pay off from late 26 onwards. In addition, any recovery in the discovery and early development market would provide a further tailwind to growth. I will return to these indicators later in the presentation and discuss them in more detail. But first, I would like to turn things over to Claire for a review of the preliminary and unaudited Q2 and first half 26 numbers.

speaker
Claire Hinshelwood
Chief Financial Officer of Evotec

Thank you, Christian, and good morning and good afternoon to everyone. On slide five, let me give you an overview of our preliminary and unaudited condensed income statement. Group revenues for the second quarter of 2026 are expected to decrease by approximately 16% to €143.5 million and for the first half of 2026 to decrease by 19% to €300.1 million compared to the same period in 2025. In DNPD, revenues are expected to decline by approximately 15% to €108.1 million in the second quarter and by 16% to €227.9 million for the first six months compared to the prior period. Within GEB, revenues for the second quarter of 2026 are expected to decrease by 17% to 35.4 million euros. And in the first half, we anticipate a decrease by 29% to 72.3 million euros compared to the same period in 2025. Unfavorable foreign exchange movements are expected to represent an additional headwind to have won revenues of 13 million euros driven by the US dollar and the British pound. Adjusted group EBITDA is expected to amount to minus 20.8 million euros in the second quarter and to minus 42.7 million euros in the first six months of 2026 compared to the same period in 2025. Turning to liquidity and the balance sheet on slide six, the total liquidity as of June 30th, 2026 stood at €465.6 million, representing a quarterly increase of €20.8 million, compared with €444.8 million at the end of the first quarter 26. The quarter-over-quarter increase was primarily driven by the gross proceeds we received of approximately $100 million related to Gilead's acquisition of our Evo equity portfolio company, Tuvulus, as well as from our recent €116 million convertible bond placement. First half liquidity further reflects the scheduled debt repayment of approximately 65.8 million euros in line with our liability maturity profile. This planned repayment reduced liquidity during the period while contributing to a lower debt position. This liquidity position combined with savings being realized from our successful implementation of the horizon transformation positions Evotec to absorb impacts such as the volatility and our strategic partnerships outlook that Christiane has described earlier. With that, I'll hand back to Christiane who will discuss the progress we're making in our commercial activities and an accelerating revenue conversion across the various components of our business.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Thank you, Claire. Before discussing the conversion dynamics we're currently seeing in the business, let us take a step back and look at the three principal creators of revenue streams. within our DMPD segment and their respective conversion cycles shown on slide seven. In our standalone business, engagements are typically focused on specific scientific services with straightforward commercial agreements and short delivery timelines. As a result, the sales cycle is fast and the period from order intake to revenue recognition generally short, often around three to six months. In the second type of relationship, integrated programs, customers engage Evotech across multiple capabilities within a broader research program. These engagements involve more complex contracting, longer delivery periods, and a wider scope of work. Consequently, revenue conversion typically occurs over a period of approximately 9 to 24 months. The third category is strategic partnerships. which represent the most comprehensive and complex form of engagement. These partnerships are individually structured, often involve extensive negotiation and governance frameworks and frequently include a combination of research services, milestone opportunities and long-term collaboration elements. As a result, the time from initial commercial engagement to meaningful revenue contribution can range from approximately 12 to 24 months. Although revenue conversion takes longer in the context of strategic partnerships, these relationships create the potential for substantial long-term value as they typically generate revenue streams over multiple years and can expand significantly over time as programs progress. Generally, as you move across these three creators of revenue streams, both the complexity and the time to revenue conversion increase. Looking at our sales to revenue conversion dynamics we experiencing in 26, we entered the year expecting improvements in commercial activity to translate into stronger revenue growth as the year progressed. As discussed earlier, approximately 15% of the difference to our previous revenue guidance relates to a conversion ambition that is no longer expected to materialize within 26. Also reflecting a more gradual pace of business expansion, while the organization remains focused on executing the horizon transformation and building the foundation for sustainable long-term growth. At the same time in the base business, including standalone and integrated programs, we have seen encouraging developments in key leading indicators from customer engagement and proposal activities all the way through net sales. During the first half of the year, Inbound inquiries increased by approximately 30%, number of proposals increased by more than 45%. In our standalone business, where both sales and revenue conversion cycles are relatively short, we are seeing these positive developments across virtually all leading indicators. Customer engagement has increased, proposal activity is growing, orders and net sales are up substantially during the first half of the year. Revenue, however, has not yet started to reflect this momentum. Given the relatively short conversion cycle of approximately three to six months, we believe this is largely a question of timing and expect these trends to translate into revenues over the coming quarters. In our integrated program business, we see a similar pattern at the front end of the commercial funnel. Customer engagement remains strong and proposal activity continues to grow. However, due to the greater complexity of these programs, orders and revenues naturally lack the trends we are seeing in customer demand. The same principle applies even more strongly in strategic partnerships. The highly customized nature of these arrangements mean that proposal activity, orders and revenues naturally develop on a longer timeline. Taken together, these indicators provide encouraging evidence that underlying customer demand and commercial activity are strengthening across all three revenue streams. The challenge we face in 26 is one of conversion timing. As commercial complexity increases, the time required for this activity to translate into revenue increases as well. That said, in the first half of 26, we were already able to shorten the average sales cycle by more than 15% to start moving opportunities through the pipeline more efficiently and supporting faster customer decision making. The commercial indicators give us confidence that the underlying trajectory of the DMPD business is moving in the right direction and that there is improved customer engagement and strengthening demand from our services. On slide eight, let us take a look on the underlying base business of our discovery and preclinical development segment, including standalone services and integrated programs, excluding large strategic partnerships to provide a clearer view of the business. We saw strong improvement throughout the first half of the year. Net sales increased approximately 28% for the first half compared with the first half of 25. This figure reflects both positive and negative change orders, giving a realistic picture of customer demand and project activity. As these activities cycle on a shorter frequency compared with strategic partnerships, it is expected that we will begin to see the results of increased activity in these areas by late this year. Additionally, proposal value in the first half of 26 increased by more than 20%, indicating a growing number of attractive value opportunities going forward. Similarly, we are seeing steady positive development of our Just Evotec Biologics segment. As organizations ranging in size from small biotechs to global biopharma companies continue to show strong interest in our innovative continuous bioprocessing offerings. Just EvoTech Biologics continues to refine its business model to maximize the benefit that customers can accrue from a continuous manufacturing approach in terms of cost, flexibility, and speed of infrastructure development. At its base, the CDMO services business is at high capacity, extending its customer base as well as its range of offerings. With the official introduction of the J-Train offering in June, customers have the potential to deploy a proprietary continuous manufacturing technology directly within their own facilities on a turnkey basis. J-Train is designed to enable significantly faster and more cost-effective deployment than traditional manufacturing expansion, strongly supporting Evotec's mission of accelerating the path to market for the industry's most innovative products. As a key example of this principle, our licensing agreement with Sandoz is progressing well in the wake of the transfer of our Toulouse manufacturing plant to Sandoz ownership last year. The relationship includes development revenues, success-based milestones and royalties for Evotec on biosimilar products in technical and early stage development. Shown on slide 10 and underlying Evotec's progress toward sustainable growth and profitability is the horizon phase of our strategic transformation. Horizon was announced in March 26 and continues to progress as planned. As a result, we expect total run rate cost savings of about 75 million euros by the end of 27, with 20 to 30% of that amount expected to be realized in 26. As announced in March, we expect the savings accrued by Horizon to start becoming apparent in the second half of this year. These cost savings, combined with the enhancements in commercial execution I discussed earlier, provide a strong foundation upon which we can erect some of the remaining elements of our strategy, including the establishment of high value strategic partnerships. Let me now hand over back to Claire.

speaker
Claire Hinshelwood
Chief Financial Officer of Evotec

Thank you. On slide 11, I would like to take you through the building blocks of our revised revenue outlook for the remainder of 2026. For the full year 2026, we now guide for grouped revenues of approximately 570 to 610 million euros at encouraged foreign exchange rates and 595 to 635 million at constant exchange rates. Adjusted Group EBITDA is expected to fall within the range of approximately minus 70 to minus 105 million euros at incurred foreign exchange rates and minus 60 to minus 90 million euros at constant exchange rates. As Christiane has said, while we see an improvement in our commercial indicators and expect to be able to close strategic partnerships before the end of the year, both will contribute only marginally to revenue this year. Let me take you through the various movements that we see to help bridge the gap on revenue guidance. When we look at our base D&PD business, we see a decline versus original expectations. This is driven by the delayed effect of existing strategic deals, as well as the conversion impacts that Christiane earlier described, which are driven by the construct of our sales portfolio, as well as the delay in the achievement of our aspirational target that we had set ourselves. Of this decline versus guidance, we would expect around 65% of this to move into 2027, with the only net reduction being the delay in achieving the aspirational conversion target. So overall, no lost business. If we move to the second bar, this is a significant bucket that we have previously discussed related to the expected new strategic partnerships. As we have previously outlined, the time to secure these deals is extremely long given their nature and can be influenced by a number of external factors beyond our control within the potential partners operating environment. We have seen in recent weeks timelines stretch beyond what was previously anticipated, meaning that any associated revenue recognition will be minimal this year. We are however confident in the quality of our pipeline and the current status of discussions and as such would see this bucket being delivered beyond 2026 with the final revenue impact being driven by the individual construct of each deal. Moving on to JEB, here we see the base JEB business continuing in line with previous guidance, reiterating the confidence in our technology offering. GEB strategic partnerships are slightly delayed versus original guidance, but here again, we would see that moving into 2027. As we are aware, it's not unusual for milestones to slightly shift, which can then result in a knock-on impact over the year-end revenue cutoff point. In terms of EBITDA impact, we see a high proportion of the revenue reduction flowing through to EBITDA due to our high fixed cost base, But where we have had the opportunity to impact our costs with an impact already in 2026, this has been reflected in the outlook. Let me now hand back over to Christian.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Thanks, Claire. Let me turn now from our strategy to the team that will deliver it and how strongly it has evolved over the past few months to bolster our commercial conversion, strengthen execution discipline and continue to drive operational excellence across the company. Over the past several months, we have significantly enhanced our management, governance and leadership team to support the next phase of Evotech's transformation. You've been introduced to all of these newcomers as they have joined. On slide 12, we would like to briefly highlight the key appointments and the talented people we have selected to fill them. In April, we were joined by Ishik Khan as EVP Global Head Chief Commercial Officer. Since joining, Ishik has made a strong contribution to building the accelerated business activity and enhancing our commercial engagement with customers I described earlier. He's working closely with our new Chief Operating Officer, Ingrid Mller, who joined in May this year and who brings more than 20 years of life science leadership experience across operations Strategy, Supply, Procurement and R&D Integration. During the second quarter, we also welcomed our CFO, Claire Hinshelwood. Claire brings a strong track record of reshaping corporate financial operations and making progress against the backdrop of challenging market conditions. Turning to the supervisory board, we have a new chairman, Dieter Weinand, who officially assumed his position in conjunction with our annual general meeting on June 11th. This year, along with new supervisory board member Wolfgang Hoffmann. Together, they bring a wealth of international leadership experience spanning the pharmaceutical, biotechnology and healthcare sectors. Their deep expertise in commercial execution, innovation, capital markets and transformation will provide valuable guidance and fresh perspectives as we continue to execute Horizon and to sharpen our focus on execution, strategic partnerships and Profitability. Before we move on to Q&A, I would like to summarize where Evotec is today and chart our course toward the sustainable growth and profitability we intend to realize over the next years. As we have said before, we expected a challenging first half of 26 and the second quarter and first half preliminary results we have just presented align with that expectation. Looking to the second half of the year, our expectations for revenue from strategic partnerships in particular, the part of our business that is most complex and time consuming to develop, have shifted recently and have led us to revise our full year 26 outlook. While the new outlook is not as robust as we had hoped, as I mentioned earlier, we do see positive leading indicators in the longer term. In spite of a difficult market, especially in the paths of our base CRO business outside strategic partnerships. With net sales up 28% year over year, in the first half we expect to see revenue from this increased activity beginning in the final quarter of the year. Combined with cost savings from the horizon transformation that will begin to become apparent later this year and will grow by the end of 27 to 75 million euros in annual run rate savings, We expect that the combination of high-value scientific offerings, improved commercial execution and disciplined financial management will keep us on track to meet our longer-term goals. To that end, in the last several months, we have created a number of new roles and filled them with experienced and accomplished individuals who will continue to drive Evotech forward. Evotech today is in the later stages of a strategic transformation that has taken multiple years to implement. There is still a lot more to do, but I strongly believe we now have the correct mix of focused scientific excellence, streamlined operations, and strong commercial infrastructure to attract, secure, and execute on a robust and diverse stream of business across our DMPG and JustEvoTech biologics segment. Thank you, and I welcome your questions.

speaker
Moritz
Cross-call Operator

Ladies and gentlemen, we will now begin the question and answer session. Anyone who wishes to ask a question may press star and one on their touch-tone telephone. You will hear a tone to confirm that you have entered the queue. If you wish to remove yourself from the question queue, you may press star and two. Participants are requested to use only handsets while asking a question. Anyone who has a question may press star and one at this time. One moment for the first question, please. and the first question comes from Brandon Smith from TD Coven. Please go ahead.

speaker
Brandon Smith
Analyst, TD Coven

Great. Thank you all for taking the questions. Maybe just two quick ones for me. I guess first, from where things stand today, I guess, do you have a goal for kind of the ratio or balance between JEB revenues and DNPD just over the next couple of years? Just trying to understand how we should think about kind of the growth of both segments relative to each other over the medium term? And then separately, I appreciate all the color on kind of the recent updates on the partnership pipeline. And I know you mentioned, you know, no new partnerships are now expected to contribute in the second half. But you said, you know, timing and deal structure should be more of a driver next year. So I guess, can you just speak a bit more to kind of the health of the partner portfolio? Maybe what gives you confidence that 27 will be better? And I guess if there's anything just about the nature of the current funnel? There's a type of assets or partners that you expect could actually inflect next year specifically, or if it's just kind of a timing consideration. Thank you.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Thank you, Brent. On the first question, we don't have a fixed ratio for JEP and DMPD for the long run. I think it's fair to say that we see growth opportunities in both segments. Also fair to say that over the last two or three years, the growth was clearly More on the JEP side, we expect this to actually going forward in the long run grow a bit faster than the DMPD segment, but there is no fixed ratio. On the health of the partner pipeline, yeah, I can give you a bit of a flavor of that because we obviously have been in discussions with partners quite a healthy number of partners since quite a while. So the way that you should look about the strategic partner pipeline is that in terms of numbers, we're somewhere between 10 to 20 opportunities here, single opportunities where we have individual either pharma or biotech companies, usually big pharma. specific topics so this could be for example in the field of obesity it can be in women's health it can be quite a few actually in kidney and renal diseases so it's across the the larger therapeutic areas and they all are based on our technology platforms so for example our capabilities in molecular glues, our capabilities in cell therapy, iPSC, omics and so forth. When you think about where they are in the life cycle, I would say roughly, roughly maybe 15% are in a very late stage where we would still expect them to close towards the end of the year. And that's important, right? While they may close, they will not have a material impact on revenues. Hence, we talk here today. Then there's a large chunk, roughly 60%, probably 60%, that is in the early to late stage term sheet discussions. So this is also pretty real conversations And then we've got the remainder, 25% or so, in early discussions or in due diligence phase. This is how you should think about the funnel.

speaker
Brandon Smith
Analyst, TD Coven

Very helpful. Thank you.

speaker
Moritz
Cross-call Operator

Then the next question comes from Christian Ehman from Berenberg. Please go ahead.

speaker
Christian Ehmann
Analyst, Berenberg

Hello everyone, thanks for taking my questions. I would like to linger a little bit more on the existing partnerships. Obviously, I'm trying to ask about the current state of the partnership with BMS. It was very successful in the past and maybe you can give us more detail on how this might look, what's going to look in the future. In addition, if I look at the numbers correctly, it looks like a little bit that JEB is actually slowing down in growth. Maybe you can Tell me if this is a correct assumption. If so, why do you think this might be the case? And attached to that the question, is JTRAIN then a direct answer to this development? Thank you very much.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Thanks, Christian. Claire will comment on the JAB question in a second. Let me first of all reconfirm Our BMS collaboration is very healthy. It has been since 2016. I did mention in the last call that we see 26 for BMS for the collaboration as a transition year. We've been harvesting a healthy pipeline in the last years all the way to 2024. We have, as I mentioned the last time, we've We've decided to refill the pipeline in 26 also based on investments into our technology platforms in the omics space. So here in particular, the proteomics and the transcriptomics screening platform. So those investments have been made and they will lead to a improvement in or revitalization of the pipeline going forward. That's why we also said last time that we expect the BMS collaboration to get back to growth as of next year and I can confirm this is still the case. And I also want to remind you that we've successfully together announced that there is one candidate actually moving into the or moved into the clinic in oncology. So all of that is pretty healthy. and a lot of concern.

speaker
Claire Hinshelwood
Chief Financial Officer of Evotec

So maybe if I pick up on the on the GEB comment, so we still see on the full year, if we were to look at the if we look at the GEB business and we exclude the Sandoz contribution to that and we exclude the DOW contribution in terms of the underlying growth of that base business, we continue to see growth Year-on-year, so no concerns there in terms of the growth. If we look to the future, then J-Train, that creates an additional opportunity for us. So I would not say it's to replace anything else, it's on top of, and in addition to utilizing the capacity that we have in-house, this creates a further revenue and profitability stream for us going forward.

speaker
Christian Ehmann
Analyst, Berenberg

Thank you. If I may ask a follow up to the BMS topic. Can we expect a model similar scope to what we've seen in the past? I believe at one point it was around 10 to 15 times of revenues.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Can you further elaborate when you say 10 to 15 times of revenues?

speaker
Christian Ehmann
Analyst, Berenberg

I mean, at one point the You released to us that the largest key account was around 12%. I assume that was BMS. And if that is true, is this a scope you can or you expect to be generated by this partnership in the future?

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

I see. OK, so I think it's certainly going to be in that range, possibly a bit a notch up compared to that number.

speaker
Christian Ehmann
Analyst, Berenberg

Okay, thank you very much.

speaker
Moritz
Cross-call Operator

And the next question comes from Charles Weston from RBC. Please go ahead.

speaker
Charles Weston
Analyst, RBC

Good afternoon. Thanks for taking the questions. If I can kick off with two. The DMPD orders for the base business you said was up 28% and various other metrics are up too. Presumably this is off quite a low base in the prior period. So could you give us a sense of where those orders are versus Normal, in inverted commas.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Well, maybe one step back, if you, I don't know whether we can go back to page seven, which gives you a little bit of a picture of the 26 commercial indicators. If you, yeah, so that page, exactly.

speaker
Charles Weston
Analyst, RBC

So I was just referring to the standalone business, if that's OK.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Exactly. So that's the upper part of that graph. But maybe one step back. I just mentioned that we have a new CFO on board, and Claire and the finance team has done a fantastic job unfolding the business and helping us to better understand the dynamics here. This is obviously not something We've been reporting in the past, so great job done by the team to help us understand the underlying dynamics here. But if you look at this or if you would look at the same picture, let's say two years ago, a year ago, you would see over the three years that this picture three years ago, two years ago has been all red. which means that we have seen a declining trend in prospects, proposals, orders, and revenues across all three levers. So when I go back to 2024 in time, this was all red. And you start to see in 25 that the standalone is actually starting to turn green with prospects and proposals. Right. And then now you see the orders going up and also the integrated program prospects and proposals. So that's a timing effect. And it also means that we've been consuming some of the backlog of previous years and actually back dates 23 probably when you think about the larger integrated programs and strategic partnerships. So you're right. 25 first half was certainly on a low level that's why when I spoke about the commercial indicators the last couple of quarters I did mention that we've seen those leading indicators we're leaving them behind we believe that they have been we've been through the trough and the fact that proposals and prospects are going up is just confirming that This seems to be a sustainable trend.

speaker
Claire Hinshelwood
Chief Financial Officer of Evotec

Yeah, I mean, I think as you look at the trend that you see in sales, and then as this chart outlines, trend that you see in sales and the trend that you see in revenue, I mean, the two, as we know, the revenue is lagging, the sales, depending on the construct that we see here of the types of deal, there is, we are coming off from a sales point of view a lower base in 25 but that didn't necessarily if you look year on year revenue 24 to 25 it didn't necessarily show up because of that phasing impact where we had some of the carry forward impact from the year before prior year sales so in every and that's the work that Christian referred to that we've been doing is we've been trying to deconstruct our sales into What are the key elements of the sales? What are the drivers for each of those elements? What are the trends that we see? What are, as we look forward, what are the leading indicators for each of them? And they all have quite, they all have different leading indicators and they all have different dynamics. So all of this is the first time that we've been able to deconstruct that and then build it anchored around the indicators that we've shared with you today. And we'll continue to do that and we'll continue to refine that. That's something that's clearly important for us. But also, as we have more transparency, then we'll be able to comment much deeper in terms of how those indicators play out in the future.

speaker
Charles Weston
Analyst, RBC

Thanks. Can I move on to the guidance? So the new guidance has been cut for this year. What is your level of certainty around this? What is the level of ambition that's built into it? What amount of wiggle room do you have in order to account for any further slippage over the remaining six months?

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

I'm going to take it, Chair.

speaker
Claire Hinshelwood
Chief Financial Officer of Evotec

Yeah, so I would say that we're confident as we look forward. In the year to go, as I talked about, these three different areas that we've shared today where we've broken down the individual sales drivers of each one. We've done really a deep analysis into each of them. We understand what the drivers are. We understand what the assumptions are and the level of likelihood that those will occur. We've also really considered the cycle timelines that Christiane's outlined here. So what will convert to revenue in the second half of the year? So I would say that we have a high level of confidence around these numbers.

speaker
Charles Weston
Analyst, RBC

Thank you. So it doesn't assume any further material new revenue driving contracts to be signed. It's kind of, it's existing. I think it presumably must be mostly existing revenue, existing contracts playing out through their revenue recognition. I don't want to put words in your mouth, but is that fair?

speaker
Claire Hinshelwood
Chief Financial Officer of Evotec

And that's what we were, the slide that we had the different timelines on, that was what we were trying to demonstrate through that slide and those conversion timelines. So if you think about if you make a sale today, depending on which of those three buckets that sale falls into, That will be an indicator of how much revenue would hit in 2026 and how much would then fall into the subsequent years. And that's what we've used as we've looked then at the second half forecast. And that's why the middle of the year is an important anchor point because those timelines of conversion in the shortest bucket, that's really the bucket that could influence the remainder of the year for revenue in the back end of the year.

speaker
Charles Weston
Analyst, RBC

Okay, thank you.

speaker
Moritz
Cross-call Operator

As a reminder, anyone who wishes to ask a question may press star and one at this time. The next question comes from Svayamampupakula Ramakant from HCW. Please go ahead.

speaker
Svayamampupakula Ramakant
Analyst, HC Wainwright

Thank you. This is RK from HC Wainwright. Thank you, Christiane and team for doing this call this morning. Just one question from me. What share of your profit, not revenue, has historically come from lumpy partner-controlled milestones? And at this point, are you re-resourcing towards recurring work so that you can manage that better?

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

That's a tough one because The nature of it is pretty lumpy and it's not a flat line. So I'm checking here with Claire if we have some guidance on the milestone contribution.

speaker
Claire Hinshelwood
Chief Financial Officer of Evotec

It can vary quite significantly over the years. I think there's obviously a difference in profile between if you have a milestone payment that drops 100% down to profitability as compared to other revenue streams that are being converted based on our fixed cost absorption levels. So I think to give you a number that would say is X percent for a specific year, that can vary quite dramatically year on year. So it would probably it would be I'm not sure it would be particularly helpful. Would need to be on an individual year by year basis because of the variability.

speaker
Svayamampupakula Ramakant
Analyst, HC Wainwright

Thank you. Thanks.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Maybe just one follow up comment to that. That's also a reason why we're trying to unfold the business here to give you better understanding that the base business is actually Thank you.

speaker
Moritz
Cross-call Operator

And we have one more follow-up question from Christian Ehmann from Berenberg. Please go ahead.

speaker
Christian Ehmann
Analyst, Berenberg

Hey again. Thank you again. I would like to go back to the J train. Maybe you can give us some idea about when this might have material impact on your revenues and earnings and how we should view, or our models at least, view pricing and potential capacity, for example, over the next years, if you're already willing to share this with us. Thank you.

speaker
Christian Wojczewski
Chief Executive Officer of Evotec

Thanks, Christian, for the question. Consider J-Train from a customer perspective also as a strategic decision. It's not something that is basically purchased in the supermarket. So those things also take their time. are an excellent technology. We've got great conversations. We've introduced it to the market recently, as you've seen. So the feedback is good, but I would not guide you to have any expectations this year that there's already a signed deal. We just spoke about the time it takes to land strategic partnerships. I would see this in a similar time dimension.

speaker
Christian Ehmann
Analyst, Berenberg

Okay, thank you.

speaker
Moritz
Cross-call Operator

Ladies and gentlemen, this was the last question. I would now like to turn the conference back over to Sarah Fakih for any closing remarks.

speaker
Sarah Fakih
Head of Global Communications and Investor Relations

Thank you, Moritz. With this, we would like to conclude today's conference call. Thank you for your participation and please feel free to reach out to the investor relations team should you have any further questions. Thank you and goodbye.

Disclaimer

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