Freeline Therapeutics Holdings plc

Good day, everyone. Welcome to the Freeline Therapeutics Business Update conference call. At this time, all participants are in listen-only mode. After the company's prepared remarks, there will be a question and answer session. To ask a question during the session, you will need to press star 1 and 1 on your telephone. You will then hear an automated message advising your hand is raised. To withdraw your question, please press star 1 and 1 again. I will repeat these instructions before starting the Q&A session. Please be advised that today's conference call is being recorded. I would now like to turn the call over to Naomi Aoki, SVP of Investor and Corporate Communications. Please go ahead.

Thank you, Operator, and thanks to everyone for joining us on the call.

This morning, we issued a press release and filed our annual report on Form 20F, with our 2022 financial results and business updates. The release and the 20F are both available on the Investors section of our website. We'll begin the call with prepared remarks by Michael Perini, our Chief Executive Officer, Pam Fultz, our Chief Medical Officer, and Paul Schneider, our Chief Financial Officer. Henning Stenecke, our Chief Scientific Officer, is also on the call and will be available for Q&A. Before we begin, I would like to remind everyone that we will be making forward-looking statements, which may include our plans and expectations with respect to our research and development pipeline, clinical trials, and financial projections, all of which involve certain assumptions and risks beyond our control that could cause our actual developments and results to differ materially from those statements. A description of these risks is in our most recent annual report on Form 20S and other periodic reports filed with the SEC. Freeline does not undertake any obligation to update any forward-looking statements made during this call. We're hosting this morning's call to provide additional context for today's announcements. Going forward, we'll not necessarily host quarterly calls. We will host calls when there are developments that would benefit from context. As always, we will continue to provide timely updates as appropriate on our progress and key milestones. I'd now like to turn the call over to Michael.