Praxis Precision Medicines, Inc.

Good day and thank you for standing by. Welcome to the Praxis Precision Medicine's first quarter 2022 corporate update question and answer conference call. At this time, all participants are in the listen-only mode. After a short remark, there will be a question and answer session, and to ask a question during that session, you will need to press star 1 on your telephone. If you require any further assistance, please press star 0. And now, it is my pleasure to hand the conference over to your first speaker today Alex Gain, Vice President, Investor Relations and Corporate Communications at Praxis. Thank you. Please go ahead.

Thank you, Paul. Good afternoon, everyone, and thank you for joining us today for our first quarter 2022 corporate update Q&A call. With me on the call is our President and Chief Executive Officer, Marcio Souza, our Chief Medical Officer, Bernard Ravina, and our CFO, Tim Kelly. Following the press releases and video update issued this afternoon, we will focus today's call on your questions. We ask that you keep to one question initially, and then please feel free to rejoin the queue for follow-up questions as needed. Before we proceed, I would like to remind you that during today's call, we may make certain statements that are beliefs, forward-looking, and subject to various risks and uncertainties. For additional detail on forward-looking statements and the risks associated with our business, I encourage you to consult our SEC filings. With that, I will now pass the call over to the operator to open up the line for Q&A. Operator?

Thank you, sir. We will now begin the question and answer session. If you would like to ask a question, please press star 1 now. Again, that's star 1 on your telephone keypad. Please stand by while we compile the Q&A roster. Your first question is from Yasmin Rahimi with Piper Sandler. Please go ahead.