5/5/2022

speaker
Rob

this year through our European colleagues.

speaker
Unknown Analyst

Got it. And then my quick follow-up is, just beyond renal transplant, will conditioning be required for CAR-T reg therapies and other chronic disease indications in either autologous or allogeneic settings?

speaker
Rob

Well, depending on the cell therapy, preconditioning is required for, I think, everything that's been required preparation of the bone marrow for the engraftment. I don't know of any examples where preconditioning has not been used. There are a number of preconditioning protocols, so there's constant work to reduce the patient burden with respect to that preconditioning. But in order to ensure adequate engraftment, typically these are being used.

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