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Operator
Good afternoon and welcome to the Agilent Technologies third quarter earnings conference call. All lines have been placed on mute to prevent any background noise. After the speaker's remarks, there will be a question and answer session. If you would like to ask a question during this time, simply press star followed by the number one on your telephone keypad. If you would like to withdraw your question, press the pound key. And now, I'd like to introduce you to the host for today's conference, or meet Ahuja, Vice President of Universal Relations. Sir, please go ahead.
Ahuja
Thank you, Paul, and welcome everyone to Agilent's third quarter conference call for fiscal year 2021. With me are Mike McMullen, Agilent's President and CEO, and Bob McMahon, Agilent's Senior Vice President and CFO. Joining in the Q&A after Bob and Mike's comments will be Jacob Tyson, President of Agilent's Life Science and Applied Markets Group, Sam Raha, President of Agilent's Diagnostics and Genomics Group, and Porig McDonald, President of the Agilent Cross Lab Group. This presentation is being webcast live. The news release, investor presentation, and information to supplement today's discussion, along with the recording of this webcast, are made available on our website at www.investor.agilent.com. Today's comments by Mike and Bob will refer to non-GAAP financial measures. You will find the most directly comparable GAAP financial metrics and reconciliations on our website. Unless otherwise noted, all references to increases or decreases in financial metrics are year-over-year and references to revenue growth are on a core basis. Core revenue growth excludes the impact of currency, and the acquisitions and divestitures completed within the past 12 months. Guidance is based on exchange rates as of July 31. We will also make forward-looking statements about the financial performance of the company. These statements are subject to risks and uncertainties and are only valid as of today. The company assumes no obligation to update them. Please look at the company's recent SEC filings for a more complete picture of our risk and other factors. And now, I'd like to turn the call over to Mike.
Paul
Thanks, Parmeet, and welcome to your first AdSense earnings call as our new Vice President of Investor Relations. And thanks, everyone, for joining our call today. Before covering our third quarter financial results, I want to acknowledge the recent passing of Dr. Tachi Yamada, a giant in our industry and a former Agilent board member. Tachi was much more than a knowledgeable, deeply involved Agilent board member for nine years. As many of you on the call already know, Tachi lived a very full life as a doctor, a scientist, as a humanitarian who was driven to help others. I know that the Agilent team is not alone and recognize that Tachi Yamada will be greatly missed and we extend our deepest sympathies to Tachi's family. Now, on to the third quarter review and our updated outlook for the year. In Q3, the very strong broad-based momentum in our business continues. The Agilent team delivered another outstanding quarter, exceeding our expectations. Q3 revenue of $1.59 billion is up a reported 26% and is up 21% core. This is against a modest decline of 3% in Q3 of last year, So we are well above fiscal year 2019 pre-pandemic levels. In addition, as another positive sign of continued momentum, orders outpace revenue during the quarter. Our growth is broad-based across all business groups, markets, and geographies. The combination of strong top-line performance and execution translate into excellent growth in profitability and earnings per share. Our Q3 operating margin is 26%. This is up 230 basis points from last year. EPS is $1.10, up 41% year-over-year. Agile success continues to be driven by our build-and-buy growth strategy and execution prowess. We are developing market-leading products and services, investing in fast-growing businesses while delivering outstanding customer service and continuing to drive profitability. Since the onset of the pandemic, we have taken actions to ensure Agilent emerges even stronger as a company. While we have yet to leave COVID-19 in the rearview mirror, our Q3 results are another indicator our actions are delivering the intended results. Bob will provide more details on end markets and geographies, but I want to briefly highlight a performance in our two largest end markets, pharma and chemical energy. We continue to perform extremely well in pharma, our largest market, growing 27% with strength in both small and large molecule segments. Our large molecule business grew roughly 52% in the quarter and now represents 36% of our overall pharma revenue, up from the mid-20s just a few years ago. In chemical energy, our business is recovering faster than expected, expanding 23% in the quarter, This is an acceleration of the momentum we achieved in the first half, and our order funnel continues to strengthen. Looking at our performance by business unit, the Life Science and Applied Markets Group generated revenue of $680 million. LSAG is up 22% on a reported basis. This is up 18% core of just a 4% decline last year. LSAG's growth is broad-based across all end markets. Our performance was led by strength in pharma, which is up 22%, and chemical energy, up 31%. All businesses delivered strong growth, led by cell analysis at 38% growth, and our LC and LC-MS businesses, which grew 22%. We continue to strengthen our position in the fast-growing large molecule market segment. During the quarter, the LSAG team launched three Infinity Lab Bio-LC systems at the well-attended Infinity Lab LC virtual conference in June. These new products further extend our LC leadership position. In addition, building on our already strong pharma offerings, we launched new compliance-ready LC-QTOF and LC-TOF solutions to our portfolio in the quarter. The Ashland Cross Lab Group posted revenue of $560 million. This is up a reported 21% and up 15% on a core basis. These results are on top of 1% growth last year. The business is benefiting from increased activity in customer labs and instrument connect rates. This is leading to more contracted services, on-demand services, and consumers' consumption across all end markets. All end markets grew mid-teens or higher, with the exception of environmental forensics, which still grew 9%. The pandemic has shown ACG to be our most durable business, with ACG grown each quarter since COVID-19 first emerged. Our customer-focused approach and digital investments continue to pay dividends. Looking forward, instrument placements and demand bode well for continuing strong performance by ACG as we drive attachment rates and increase customer lifetime value. The Diagnostic Genomics Group produced revenue of $346 million up 44% reported and up 37% core, compared to an 8% decline last year. The growth was broad-based across product lines and regions and was led by our NASD GMP oligo business. The ramp of our facility in Frederick, Colorado continues to go very well. The quarterly results exceeded our expectations, easily surpassing the $50 million revenue milestone. While one quarter does not make a trend, our team has done a tremendous job increasing output in a high-quality manner. This gives us increased confidence in our ability to exceed the $200 million annual run rate in revenue with existing capacity. In addition, the train B manufacturing line expansion is well underway and on schedule. Our genomics instrumentation and consumables businesses rebounded strongly in the quarter, as did our pathology-related businesses. For the first time in several quarters, we saw diagnostic testing above pre-pandemic levels. While we are watching the Delta variant very closely, to date, we have not seen a meaningful negative impact in testing values. I also want to highlight our performance in China. While still less than 10% of DGG revenue, our China business grew 50% in the quarter. We continue to see tangible progress in building a stronger China market position. In Q3, we signed our first ever companion diagnostic development services agreement with a China-based biopharma company. Earlier this month, we also announced the initiation of in-country manufacturing for our Sure Select product line. We are very bullish about long-term growth prospects in China for our DGG product and services offerings. In addition, the integration of the Resolution Bioscience team is going well, and we are very pleased to enter and expand our participation in the fast-growing NGS-based cancer diagnostic market. It was a busy quarter at Ashland, so I have a few other achievements I'd like to share with you. Last month, we published Ashland's 21st Annual Corporate Social Responsibility Report. At a time when some are just starting to look at issues like sustainability and societal impact, this has always been a key part of who we are as a company. We've been addressing these issues since our founding more than two decades ago. I would encourage you to review our report on the Agilent website. We're also very pleased to receive recognition of the Great Place to Work in the United States by the Great Place to Work Institute. This result is just one more example of Agilent having a highly engaged and energized team And as you know, teams with high engagement win in the market. Looking ahead, building on another excellent quarter and the momentum we're seeing, we expect the business to continue to perform well as we close out what we believe will be an outstanding fiscal year of 2021. As a result, we are once again raising our full-year revenue and earnings guidance. Bob will share more details, but we're expecting a continuation of our excellent top-line growth and earnings generation. While the world has yet to fully emerge from the global pandemic, Agilent is well-positioned to deliver excellent results again in the fourth quarter. I remain very proud of the Agilent team's ability to consistently deliver for our customers and shareholders. Thank you for being on the call today and look forward to your questions. I will now hand the call off to Bob.
Tachi Yamada
Bob? Thanks, Mike, and good afternoon, everyone. In my remarks today, I will provide some additional details on Q3 revenue and take you through the income statement and some other key financial metrics. I'll then finish up with our updated outlook for the fourth quarter and the full year. Unless otherwise noted, my remarks will focus on non-GAAP results. As Mike mentioned, we had an excellent result in the third quarter. Revenue was $1.59 billion, reflecting reported growth of 26%. Core revenue growth was 21%. Currency added 4.5% for the quarter, and M&A added half a point. In addition, COVID-related revenues were in line with the prior year. All end markets performed well, with pharma and chemical and energy as standouts versus our expectations. Our largest market, pharma, grew 27% during the quarter after growing 2% last year. The performance was led by the continued strength in our large molecule business, growing 52%, while our small molecule business grew mid-teens. And all regions in the pharma market grew double digits. Our large molecule business was driven by our NASD division and demand for LC and mass spec instrumentation and solutions, while our small molecule business was primarily driven by QAQC refresh. Chemical and energy also performed well this quarter with 23% growth. Even after accounting for the comparison against the 10% decline last year, this was clearly our best quarter since the onset of the pandemic. This result was driven by increasing momentum and demand for advanced materials and the general global economic growth. Our view is that the chemical and energy market still has additional room to grow moving forward. The diagnostics and clinical market grew 28% against the decline of 10% a year ago, our softest quarter last year. We are very encouraged with the continued recovery in the market as our genomics and pathology businesses saw very good growth. On a regional basis, all regions grew, with China up 41% and America's delivering 38% growth. In the academia and government market, we delivered 12% growth as most research labs continue to open globally and expand capacity. On a regional basis, Europe led the way. The food market continued its double-digit performance, growing 12% on top of growing 1% last year. Food manufacturers continue to invest in increased testing to ensure quality and authenticity. A developing cannabis testing market, primarily in the U.S., also contributed to growth in this market. And regionally, the food market was led by the Americas and Europe. Rounding out our key markets, environmental and forensics came in with 5% growth. On a geographic basis, all regions demonstrated solid growth, led by the Americas at 32% and Europe at 23%, both exceeding our expectations. The performance was broad-based across all markets. And as expected, China was up 8% on top of 11% growth last year. All three business groups grew in China during the quarter. Pharma, chemical and energy, and diagnostics were the key drivers. Now turning to the rest of the P&L. Third quarter gross margin was 55.9%, up 80 basis points from a year ago, despite roughly 40 basis points of headwind from currency. Our strong top line, some positive product mix, coupled with the strong execution from our operations team drove the year-on-year improvement. And our supply chain team is doing a tremendous job getting our products to customers, despite the increase in demand. Growth margin improvement or performance, along with continued operating expense leverage, resulted in operating margin for the third quarter of 26%, improving 230 basis points over last year. Putting it all together, we delivered EPS of $1.10, up 41% versus last year. Our tax rate was 14.75%, and share count was 306 million shares, as expected. We delivered $334 million in operating cash flow during the quarter, showing a strong conversion from net income and up more than 15% from last year while crossing the billion-dollar mark in nine months. During the quarter, we returned $172 million to our shareholders, paying out $59 million in dividends and repurchasing roughly 800,000 shares for $113 million. Year-to-date, we've returned $829 million to shareholders in the forms of dividends and share repurchases. And we ended the quarter with $1.4 billion in cash, $2.9 billion in outstanding debt, and a net leverage ratio of 0.8. Accounting for our Q3 performance and improved outlook in the fourth quarter, we are again raising our full-year projections for both revenue and earnings per share. We are increasing our full-year revenue projection to a range of $6.29 to $6.32 billion, up $125 million at the midpoint from previous guidance and representing reported growth of 17.8% to 18.4% and core growth of 14.5% to 15%. Included is roughly three points of impact from currency and a small amount from M&A. In addition, we're on track to deliver roughly $100 million in COVID-related revenue in fiscal 2021, in line with our expectations from the beginning of the year and flat to last year. We expect to continue our strong operating leverage, and so we are increasing our fiscal 2021 non-GAAP EPS to a range of $4.28 to $4.31 per share, up 30% to 31% for the year. This translates to fourth quarter revenue ranging from $1.63 billion to $1.66 billion. This represents reported growth of 10% to 12% and core growth of 8.5% to 10% on top of the 6% growth in Q4 of last year when we started to see early signs of recovery from the strict lockdowns. In addition, while COVID revenue is roughly flat year on year for the full year, Last year's fiscal fourth quarter represented the high watermark in our COVID-related revenue. And as a result, we expect to see roughly a one-point headwind due to COVID revenue in the quarter. So our core growth, excluding COVID, would be comparable to 9.5% to 11%. We are forecasting higher expenses in the fourth quarter as we invest to maintain our strong momentum, but expect continued operating leverage in excess of 100 basis points. Non-GAAP EPS is expected to be between $1.15 and $1.18, with growth of 17% to 20%. Now, before opening the call for questions, I want to reiterate that we continue to see good demand in our end markets, have solid momentum in all our businesses, and expect to close the year extremely well. We believe our strategy is the right one for Agilent, but we couldn't achieve these results we've been producing without the excellent execution by the team. With that, Parmeet, back to you for Q&A.
Ahuja
Thanks, Bob. Paul, if you could please provide instructions for the Q&A now.
Operator
Definitely, sir. We will now begin the question and answer session. If you would like to ask a question, please do so by pressing star 1 on your telephone keypad. Again, that's star 1 on your telephone keypad. However, if your question has been answered and you wish to remove yourself from the queue, please press the pound key. please stand by while we compile the Q&A roster. Your first question is from Tycho Peterson with JP Morgan.
Tycho Peterson
Hey, good afternoon. Congrats on the quarter. Mike, I want to start with the China outlook. You know, I know in China there's been, you know, a fair amount of noise about, you know, companies being able to get products in country, you know, ports being, you know, shut down, terminals shut down. So can you maybe just talk to kind of some of the near-term dynamics in China? And it sounds like trade tension is also getting worse with the buy China policy. So how do you think about that, you know, over the next couple of quarters?
Paul
Yeah, sure. Thanks for the congratulatory comments, Tycho. And we really actually continue to feel quite good about our performance in China. As Bob and I mentioned in a call script, I think 8% up on 11% last year. And I think our stack growth rate is around 19% of Q3. It's actually up over our stack rate of 17Q2. We're seeing this good, strong pharma and C&E demand in China. Now, and the funnels really remain quite robust. And I think now getting to your specific question, we're not seeing any significant changes in terms of ability to get product in. I mean, there's been a lot of noise for years, I have to say, between the United States and China, yet the business seems to somehow get transacted. So, Bob, I think we're not really overly concerned about those dynamics. And You know, we did have somewhat of a little bit of shipment interruption, you know, as some of our academia government customers had to work through a VAT tax exemption change. But I think that was relatively minor impact on the P&L. So clearly we're monitoring those developments, and you have to continue to work to make sure you've got your logistics flowing through the country. But we've always been able to find a way and are not overly concerned about it as of this point.
Tachi Yamada
Yeah, I would say, Tycho, we continue to invest in China, as we mentioned in the call. And, you know, there are always bumps here and there. But long term, we feel very good about the business in China.
Paul
Yeah, and I just have one other thought here, Tycho, is relative logistics. We have invested into a number of forward-looking stocking locations over the last few years. That really has paid us dividends because we're less dependent on stuff coming directly in via the port because we have a lot of in-country inventory.
Tycho Peterson
Okay, that's helpful. And then, you know, it sounds like you've got a lot of underlying momentum. I know you don't like to talk about the order book, but any preliminary comments you can make on 22 at this point, you know, the street has you up about 6.5%. Curious, you know, if you think that's a reasonable bar and any comments on where you think margins may go next year.
Paul
Yeah, thanks, Tycho. So, as you might imagine, I'll probably sidestep that question a little bit in terms of specifics, but what I can tell you is that we feel really good about the momentum of the business. The order book is continually strong, and that's as of today, where we got the latest view of early orders through August. So, order momentum remains there. As I mentioned in our prior earnings call, you know, we feel really good about it to meet and exceed those long-term goals we put out and margin goals. I think that's where we stand right now is, you know, we'll get to that in November, but, you know, we're feeling good about the trajectory of the business momentum we built here.
Tycho Peterson
Okay. Thanks. I'll let others hop in.
Operator
Your next question is from Brandon Couillard with Jefferies. Hey, thanks. Good afternoon.
Brandon
Good afternoon, Brandon. Mike, maybe to start with the biopharma business, I mean, 50% growth in large molecules, pretty impressive. Can you just elaborate on the sources of growth there and what that would look like if you back out the NASD contribution?
Paul
Yeah, sure. And then I'm actually going to invite Bob, and I also want to have Jacob make a few comments on some of those new introductions here. I think I used the word broad-based at least five or six times, maybe ten times in my prepared remarks, and we're seeing that in biopharma. So we've got across-the-board double-digit growth happening here. Cell analysis, LC, LC-MS, other platforms are going to biopharma along with our consumers and services. And then, to your point, really outstanding growth in NASD. While NASD was a big contributor, it was an asthma-wide story. And, Bob, maybe you can answer this specifically on the numbers.
Tachi Yamada
Yeah, and, Brandon, to your point, you know, total in large molecule was 52%, as I mentioned before, but even if you back out, the NASD businesses still grew in excess of 40%. So very strong business on NASD, but it shows that the rest of the business, both instrumentation as well as the consumables pieces and the other elements on, you know, the pharma-associated revenue in diagnostics and genomics, also very strong business in it.
Paul
And, Brandon, I just wanted to maybe have Jacob jump in very quickly because we have a continued drumbeat of new introductions into this space as well, which has been the focus and prioritization of our R&D pipeline. And, Jacob, I know we had two big introductions in Q3 as well.
Brandon
yeah thanks for that mike and as you said you know at the end of the day i think we talked about in that 70 of our portfolio about that was really focused on biopharmacy i'm really happy to see that momentum we have right now and as you also mentioned in prepared remarks you know i'm i'm very pleased what we did with the bio lc portfolio uh in fact we had and um and one of the big of our momentum is that with that bio lc that we introduced here a few months ago um and we had a virtual conference with more than the 1000 customers participating and we had more than 25 external scientific speakers which i would actually say i know it's the best in industry by far so that the that the introduction is actually creating quite a lot of momentum and it allows us to play for all the bio nerd biocompatible space for the 2d lc but clearly also into the into the mass spec with the box back in the end of it And we also mentioned compliance, the FDA part 11, compliance is another very important part that most of the biopharma sees as a requirement to do business with them. And we have invested in this for quite a while. So we ensure the data integrity, the audit readiness and storage of data have the right level of security. And right now, we have the offering both supporting our LC, but also all our major mass spec instruments and also in spectroscopy with the recent announcement here of the top and the future of informatics solutions. So, right now, we have a very strong portfolio, and that truly drives our growth. Well, I can continue talking about the cell analysis, but I will leave that for now.
Paul
I better bounce it back to Brandon. Hey, Brandon, thanks for allowing us to do a little bit of advertising on the Agilent portfolio strength. But back to you, Steve, any additional questions?
Brandon
Yeah, I think just touching on maybe if we could just elaborate on the small molecule market. You mentioned kind of QAQC refresh. Curious what we might be in there and what you think the market is kind of growing for small molecules relative to your mid-teens.
Paul
It's our view that there's always a replacement market going on in the small molecule space. And sometimes it picks up a bit more. But I think we're in that phase right now. I wouldn't say it's a huge acceleration. It's just solid.
Tachi Yamada
Yeah, I was going to say, you know, Brandon, as we think about this, you know, prior to the pandemic, we were probably slower growth than normal where some of the QA, QC, you know, refresh was probably elongated. And now we're starting to see that pick back up. And, you know, that typically is an 18 to kind of 24-month kind of cycle. And I would say we're still in the, you know, the beginning of that. And so feel good about the continued performance of the refresh cycle going forward. Great. Thank you.
Operator
Your next question is from Vijay Kumar with Evercore ISI.
Vijay Kumar
Hey, guys. Congrats on the strong print this afternoon. Thanks, Vijay. Maybe, Mike, maybe on my first question here, Resolution Bio, the deal that you guys did, Did that come in line with expectations? I'm just curious. The 50 basis points contribution seems a little light. Is there some ramp up phase here that's involved? And maybe just talk about what the deal does to you and how it adds to the corporate growth rate here.
Paul
Yeah, so you do some very good math. So it's about half a point of reported growth, right, Bob? And I'd say relative to Q3, probably a little bit behind the revenue as we learn more about this business. There's some elements of a little lumpiness. So we're feeling pretty good about how the business will finish, but we're expecting a lot in the fourth quarter. I think this is a story of continued acceleration of growth in 2022 and beyond. And we're just super delighted by the early days of how the teams feel about being part of Agilent. And then we're really building scale around this business. So I think, you know, it's still relatively small part of the overall revenue picture today for Agilent. And we knew that going in, I think it's roughly a 60-ish kind of million. But, you know, we expect, you know, really strong growth rates in the coming years and Again, we really feel like we're off to a great start with this team. We're just interacting with Mark Lee, who's the founder, co-founder of ResVision Bio. He's really happy about the capabilities that we're bringing to his business to further scale it. Early days, but, you know, feeling pretty good about things.
Tachi Yamada
Yeah, I was going to say, the other thing is, you know, obviously we're just now, you know, having more and more conversations with our existing CDX customers, and the power of being able to have our established CDX business on the IHC side coupled with NGS-based technology I think is going to be a real significant competitive advantage for us going forward. So very excited about this business going forward.
Vijay Kumar
That's helpful, Mike. And Bob, one for you on expenses. In the year-to-date operating expense as a percentage of revenues, you guys are in low 30s, sub 31%. That's well below your historical level. I guess my question is, is this all just associated with volume leverage rate given the strong organic performance year-to-date, or... Are there some timing elements on expenses that's aiding you? And if there are, how should we think about those factors coming back in that 22?
Tachi Yamada
yeah vijay it's a great question and and uh i think if if you uh remember maybe a year ago we talked about some of these expenses that were going down um and our goal was not to have them come back to the same levels that they had and these would be in areas around travel but also leveraging our digital capabilities and what we've been able to do is be very successful certainly volume is our friend um and uh the leverage that we've been able to to drive across across all three of our business groups has really helped. But if you look at our year-over-year elements around travel and costs associated with marketing programs and digital investments, our digital investments have gone up, but the actual return on those investments has actually gone up. And in fact, Jacob just highlighted one of the programs that we had and so those are our goals are for those to continue. They will continue to ramp next year to come back. but not near the level that they had come prior to the pandemic. So we do think that there's a fundamental margin improvement associated with these expenses, and that's why Mike talked about kind of our long-term margin expansion story is intact. It's not going to be 200-plus basis points like it was this last quarter, but certainly feel good about our continued ability to drive margin expansion.
Paul
Hey, Vijay, this is Mike. If I could just add one additional comment, too, and it hopefully came out in our prepared marks, but we're not holding back on investing for growth. So we were quite pleased with the margin performance, but it didn't come at the expense of our ability to grow down the road.
Vijay Kumar
That's extremely helpful, Mike. Congrats again. Thank you. Thank you.
Operator
Your next question is from Doug Shankle with Cowan. Your line is open.
Doug Shankle
Hey, guys. Good afternoon. Actually, can I just build off of that last question with a quick follow-up? Again, acknowledging and recognizing you're not going to guide on 2022 today. I'm just wondering, though, at a high level, should we assume that incremental margin is going to be a little bit lower than normal next year if we're assuming a normalization of activity in a post-pandemic world? I heard what you said about areas where you're not going to need to invest as much, but at the same time, you are investing in growth. Just mathematically, the incrementals need to be a little bit lower than normal next year.
Tachi Yamada
Yeah, we're still building our plan, but our intent is to still be able to drive that margin expansion. I will say that, you know, we are having our new train B in NASD come online, which is We'll add a little pressure to it, but I think we've been very good about being able to do 30% to 40% incrementals and sometimes even higher than that when the margin comes in, and I don't see any reason why we shouldn't be able to continue to do that. Doug? Okay. Super helpful. Maybe what's underlying your question is, you know, inflationary pressures and activities around that. And, you know, I would say that, you know, we didn't see any material impact. Obviously, there is some, but we're planning to manage that going forward.
Doug Shankle
Yeah, no, that's dead on. It's supply constraints. It's inflationary pressures. It's the hope that we're traveling a little bit more and there's real conferences and real site visits, things like that. So that's the spirit of the question, just making sure that to capture those dynamics, we don't have to think about something other than that 30 to 40 traditional time range. So that's helpful, Bob.
Paul
I would just add, Doug, that we're working on 22 now. Sorry to interrupt, Doug, but I would just say that some of our programs and such are really geared towards making sure we can manage our way through this in 22. So we're on this already. Got it.
Doug Shankle
Okay. In terms of full-year guidance, as has been noted a few times, you increased the outlook by more than the magnitude of the Q3B. I guess I'm just wondering what gives you confidence in this change. Is it backlog data? Is it pacing across the quarter? Is it activity through the first month of the quarter? Maybe it's all of the above. And maybe more importantly, you checked everyone. Okay, perfect.
Paul
Yeah, no, Bob and I are smiling in the room here, and I think we probably did a checkmark on all first of those three things you mentioned.
Doug Shankle
Okay. And then throughout the year, you've consistently prioritized It definitely makes sense to skew the error bars a bit more conservatively when you set your targets given the state of the world. That said, given how well you performed relative to those targets and recognizing we're not out of a pandemic, but we got a little more experience with it at this point, is it fair to say that you're at the point where you could adjust the philosophy a little bit and maybe kind of change the positioning of those error bars as you set guidance moving ahead?
Tachi Yamada
Yeah, I think that's fair. I think, you know, what we've tried to do is set prudent guidance, as we've talked about in the past. But certainly as we've – and our customers, more importantly, the market is getting used to kind of dealing in a COVID world. There's fewer variables to be able to kind of understand. And, you know, I would look at just kind of what we did in Q3. Q2 to Q3, you know, we dramatically increased our Q3 guidance and then did the same thing here for Q4. So, you know, I think our visibility is improving. You should take that away for all the things that you kind of rattled off. Certainly, you know, the momentum that we're seeing, you know, the general economic improvements and so forth. But as you mentioned, you know, there's still a Delta variant out there. And so while, as Mike mentioned, we haven't seen any impact of that yet, you know, we also recognize that that could change during the course of the quarter. So we're trying to take all those kind of factors into account, but also try to provide some realistic guidance going forward.
Doug Shankle
Okay. All right. Thanks again, guys. Yep.
Tachi Yamada
You're welcome, Doug.
Operator
Your next question is from Derek DeBruin with Bank of America.
Tachi Yamada
Hello and good afternoon. Hey, Derek. Hey. Can we talk a little bit about environmental and sort of that? And sort of I want to dovetail that question to – I know it's probably a little bit early, but – any signs of how we should think about the gc portfolio picking up um are you just replaced you know is it just sort of like ketchup spending right now in the industrial um or you know any initial indications that that the replacement cycle that you were you were on you were going you were in the midst of prior to the pandemic is likely to restart
Paul
Hey, how do I take the first one? And Bob, I mean, Bob, and then Jacob, you may want to add additional comments here. But let me talk about the question around gas chromatography. So we are seeing that. And that's really behind a lot of the fairly bullish comment if you will, around C&E space. So we're seeing it in our GC revenue, and we're also seeing it in our GC order book. And I've been very reluctant to call that, hey, we think this business is now in a situation of returning to growth. That reluctance has now passed. I think we're now into what looks to be the start of some really good potential business on our GC side as that replacement cycle turns back on. And, Jacob, I know you're a lot closer to the details of Miami. Anything else you'd add to that?
Brandon
Yeah, Mike, you're absolutely right. I think first of all, I think Bob mentioned that also the chemicals and engineered materials markets are certainly on fire right now. We see a lot in Semicon and in mining industry, including, you know, late term for batteries. But we also see the traditional petrochem markets really start to see some momentum now. And, you know, there's a lot of talk about the future of Petrochem, but this market is going to stay for quite a long. And I think that all the analysis show that there'll be newer cycles here. So we see investments coming into this market right now. And the new market that's also coming along is renewable energy. which will also use many of our technologies. And we see a great opportunity there also in the future. They're still in development phase, but as you know, there's a lot of investments going in here. So we are participating in that also. So we see a lot of opportunities in DC and the DC is actually seeing a momentum both first in the chemical markets, but now into the energy markets.
Tachi Yamada
Okay. So following up on that. So, you know, you're feeling good about sort of your more industrialist experiments, even with some of the choppiness in the Chinese market, some of the data there. So are you seeing, is it the U.S. and Europe that's starting to bring more, or is it just you're seeing a turn on that one? And then where were we? What remind me in annoying baseball analogies where we were in innings on the GC replacement cycle?
Paul
Yeah. So, Bob, I think it's fair to say that there really is no difference across the regions. I mean, China actually was an area of strength for us in C&E. And I think we're seeing good strength globally, which I think points to the importance of global economic outlook for this segment. And I'd say we're probably earlier middle innings. I'm going to pause there for a while because we had a great run going with the new portfolio, but it paused. So I'd say we're like early innings, middle innings?
Tachi Yamada
Yeah. I would say, Derek, just to give you a frame, China was more than twice the China C&E market was in line with the overall C&E growth rate that we saw.
Ahuja
Thanks. Thanks for your question.
Operator
Your next question is from Dan Leonard with Wells Fargo. Your line is open.
Tachi Yamada
Thank you, and good afternoon. Mike, I was hoping you could address the 5% to 7% core revenue growth model that you've introduced in December. Is that still relevant, or do you think something's fundamentally changed in the markets from that time period?
Paul
I'd say it's relevant until we change it. So I'm not ready to on the fly here, you know, revise our long-term growth. But as you may recall, in our December outlook, we said, think about us being more at the high range in that area. And I think I've I think that was the first time we put a seven out there in any type of long-term growth guidance. I think what's changing is the nature of our portfolio, which is we're beginning to build very quickly much bigger positions in faster-growing segments. And I think it's probably fair to say that the – the pharma market, in particular the biopharma market, remains very robust. But again, we're sticking with those long-term growth goals at this point in time.
Tachi Yamada
Yeah, I would say, Dan, to build on what Mike is saying, particularly the pharma market, we do feel that that market, and in fact, Mike talked about it in his prepared remarks that we're emerging as a stronger company. We do think that the pharma market, really driven by that large molecule area, is a faster growing market coming out of the pandemic than going into it. And I think if we look at where our investments are and the performance that we've had in particularly the large molecule – now, again, small molecule has been doing very well – um that that in and of itself um would elevate that overall long-term growth rate to be you know faster than what we saw going in which which certainly helps us given that is that's our largest market so i'll leave it at that okay that's helpful clarification and in just a follow-up on china can you elaborate further on the drivers of that 50 growth rate you called out for for dgg in china
Paul
Yeah, I'm going to invite Sam on this call. He hasn't had a chance to work today on this call. So, Sam, your thoughts on what's been going on in China? I was doing a little bragging on your growth right there.
Brandon
Yeah, Mike, happy to give more perspective on China. You know, we actually had a good quarter across the board for all of our business groups within DGG. Specifically, we've continued to see Real momentum in clinical diagnostic testing led in pathology. We've seen really good pickup of our PD-L1 diagnostic, a companion diagnostic there as we continue to train, you know, more pathologists there in use and so forth. Genomics also had a really, really good quarter, both on the consumable side and, you know, we've also just recently announced within the quarter of the launch of our new V8 exome, which is being well received in China and globally. And I'll tell you, one of our absolute strengths in China, as it is elsewhere, remain our core NGS and genomics QC portfolio. So all of those elements, along with Mike, as you mentioned now, you know, the signing of our first companion diagnostic development agreement with the biopharma there, I think foretell a continued story of strength in China for DGG.
Paul
And just to build on Sam's comments, I mean, we've been working really hard the last several years putting in the right foundational capabilities, building the right commercial channel, the right ability to handle diagnostics products ourselves. So I think it's really great to actually see those investments starting to pay off in near-term growth.
Tachi Yamada
Appreciate all that, Keller. Thanks, everyone.
Operator
Mm-hmm. Your next question is from Patrick Dinelli with Citi. Your line is open.
Patrick Dinelli
Hey, thanks for taking the questions, guys. Mike, maybe one on the chemical and energy side to follow up on some of the earlier questions. I know that's one where you pretty closely keep an eye on the order book, and your confidence kind of goes with that. Are you getting more visibility as the order book builds there? I'm just trying to compare it to even pre-pandemic, mid-pandemic. I know you guys had a pretty short leash on it in terms of how you would guide for that segment, how comfortable you would allow yourselves to get. Just wondering how the order book is looking there relative to some of the past quarters and how you're feeling about that segment.
Tachi Yamada
It certainly seems like the tone is pretty positive here.
Paul
Yeah, no, I'm glad you picked up on that. We really wanted that to come through in the call. And I think the confidence is coming from not only the revenues that we reported, but as Bob mentioned, in general, and I think it also holds for C&E, we just have much better visibility into our funnel. And, you know, you may recall I was talking a lot of, in prior calls, I talked a lot about a conversation we're having with customers and we knew there was activity, but now that conversation is turning into orders. Um, so, um, So we're feeling much better about the trajectory of the C&E space. And, you know, I've historically been very, very cautious to give any real kind of positive trends in this area. But I think we've seen enough over the last few quarters. And what we're seeing with our customers in the order book, you know, is really the basis for this confidence. And, again, it's tied to not only the pent-up demand they've had in terms of needing to replace agent equipment in their laboratories. But they also, what we hear from our customers, they're much more confident about where the global economy is going. So they're willing to make investments. I know there's a couple of pauses here and there. There'll be some ups and downs because of outbreaks here and there of COVID. But in general, the trend remains very positive. I think as Bob mentioned earlier, our customers have learned to deal with this. So Bob, we talked a lot about this. Anything I missed there? Nope. Okay.
Patrick Dinelli
That's helpful. Appreciate it, Mike. And then on the diagnostic side, it is given commentary that you guys are above pre-pandemic levels. Can you just talk about the pace of the recovery in the quarter and then expectations for the further ramp from here? I just want to clarify and make sure you haven't seen any impact in Delta up until, I guess, this week. I just want to make sure I have that clear. Thank you.
Tachi Yamada
yeah yeah i mean we saw continued recovery i think we mentioned at the beginning at the end of q2 that you know we were kind of at pre-pandemic we exited there the average was still below and that steady improvement across across our business across really across all all of the regions continued into q3 and by the end of q3 we were above And, Patrick, to your specific question about Delta, we have not seen any impact to date associated with that. Great. All right. Thanks, Paul.
Operator
Yep. Your next question is from Mike Sykes with Goldman Sachs. Your line is open.
Mike Sykes
Oh, hey, guys. Thanks for taking my question. Congrats on the quarter. Sure. Thank you. Just on ACG, you guys had a pretty impressive operating margin, over 29% for the quarter. I'm just wondering what you feel about sustainability of those margins and then any progress that you've made on attachment rates in that business. I know you mentioned a little bit in your prepared remarks, but any additional color on that would be helpful.
Paul
Yeah, I think I'll pass it on to Porik, who can provide some additional color on the ACG and answer your questions. Go ahead, Porik.
Porik
Yeah, great. Thanks, Mike. And we're getting back to more normalized service support with our customers, which has more costs associated, of course, with travel. But we're starting to see a creative margin in Q3, and we're seeing that going to improve in Q4, so very, very strong on that. In terms of attach rate, we're seeing increased attach on our services and consumables. And of course, with the larger install base, this bodes really well for the future as more attached rates for services and consumers will be available to us. So very strong outlook.
Tachi Yamada
Yeah, hey, and Matt, maybe just to build on what Porig is saying, you know, in terms of sustainability, we feel very, very, very good about the ability to continue to sustain those levels of margin. It gets back to the work that our service engineers do in servicing our customers is mission critical for our customers, keeping those labs and those instruments up. And our ability to continue to invest in digital as well as, you know, be there onsite on the labs or with the labs is really important. You know, one piece that I would add is, you know, we continue to invest in that digital, as I mentioned before, and our online orders actually grew faster or revenue grew faster than the overall ACG business, which actually speaks to our continued relevance in that space. And obviously that's good for our customers in terms of either doing business with Agilent, but it also helps from that margin perspective as well.
Mike Sykes
Great. Thanks for that call. It's very helpful. And then just one more on C&E. I know you've answered a lot of questions on it already, but I'm just wondering how the competitive landscape might have changed. I mean, obviously, it had a challenging time during COVID. It took a while for it to recover, and now it's certainly in recovery mode. I'm just wondering, as you look out at the competitive landscape, have you seen some competitors' slow investment, and therefore, there's some share gain opportunities in that growth that you're seeing? I don't know where they slowed.
Paul
I'm not sure they were investing for that segment. So, and we're not seeing much happen on the competitive front. We're by far, this is, we're the clear leader in this space. We've continued to invest in our core portfolio pre and throughout the pandemic. So, as you can tell, I'm pretty bullish about our ability to outgrow the competition in this space.
Tachi Yamada
Yeah, let me add, you know, It seems like a long time ago, but, you know, we launched two new GCs back in 2019, both at the high end and a mid-range GC. And we talked about one of the reasons that we did that is we've got leadership position in the GC market. But when you look at it, we're over-indexed to the high end. And so the ability for us to be able to have this mid-range, I think, was really critical. And, you know, we're starting to see that benefit. And maybe Jacob wants to jump in the conversation.
Brandon
yeah exactly you have to rely on on the dc and and our strength and our beast dc but i i think we should also mention our spectroscopy business and the and the ictms where we have done a lot of work also icp oes and ms where we've done a lot of work that is that have a very strong market share for the material science and uh we continue to take market share in that that space also so i think you see us being very strong here and we we have also uh and size that we will continue to invest into this market going forward. So there's a lot more there for the customers going forward.
Mike Sykes
Great. Thanks very much.
Operator
Your next question is from Joshua Waldman with Cleveland Research. Your line is open.
Patrick Dinelli
Hi. Thanks for taking my questions. Just two for you. Mike, you mentioned overall orders, outpaced sales in the quarter, and it sounds like book to bill in the LSAG business was likely positive. Just wondered if you could provide us with your assumptions for core growth in the LSAG business in the fourth quarter. And then as we look beyond FY21, given the broad-based strength you've spoken about on the call today, I guess, is it fair to assume that, you know, as we look to FY22, this business should likely grow, you know, something above kind of a low to mid-single-digit longer-term average?
Tachi Yamada
Yeah, let me talk about the fourth quarter, and I'm not sure we're going to answer the last one just yet as we're going through our plan. I had to try. Yeah, yeah, yeah, no, it's a good try. But I would say for Q4, you are – You're accurate in the belief that our book, the bill, was positive for the quarter. And, you know, if we think about Q4, our guidance comprehends, you know, high single-digit, low double-digit growth for the LSAG business core growth. And so I'll leave it at that. Got it. And it seems like year-to-date pharma has outperformed what you expected coming into the year. I just wondered if you could comment on any kind of current thoughts you have around the potential magnitude of any year in budget flush, I guess, given – It seems like investments from these customers have been fairly consistent, consistent and strong throughout the year. Does that kind of deflate any kind of year-end spending? Yeah, we'll address that, you know, in our Q1 call. But to your point, we've been pleasantly surprised, and it has continued to be more stronger than what we've anticipated throughout the first three quarters. And what I would say is we don't expect that to slow down any in Q4 either.
Doug Shankle
Got it. Thank you.
Operator
And your last question is from Jack Meehan with Nefron Research. Your line is open.
Jack Meehan
Thanks. Good afternoon. You talked about a job that your team is doing managing the supply chain. I was wondering if you could elaborate on a hotspot you're seeing in terms of inputs, shipping, or labor. And when you look at the fourth quarter guidance, is that you know, are you taking any more prudence or conservative type approach based on what's going on in the supply chains?
Paul
Yeah, I mean, this has been a lot of discussion. I think everybody's talking about supply chain constraints, you know, on a global basis. And it's been a challenge for us. But as Bob noted in his call script, our team has just done a tremendous job, you know, getting the Agilent products to our customers. And we're really good at this about managing situations. We've been working on these a number of commodity areas for some time. And we also have done things such as, you know, identifying and changing alternative sources of supply. So we've been able to do that. We've had last-minute changes to notification from logistics suppliers that they won't pick up our boxes. And so we switched to another supplier. So we've been able to manage our way through that. And, you know, And it was conspicuous. It was absent in our call script, a lot of details, because while we continue to monitor it, we really don't believe it's a material risk to the company at this time. And we feel like we factored all that into our guide for the fourth quarter. And, Bob, I know that you've been up close studying this as well. Anything else you'd add to that?
Tachi Yamada
Yeah, the only thing I would say is, you know, it's the usual suspects that other folks have called out, things like residents and chips and things. Our team has done to date an outstanding job of being able to continue to satisfy demand here. And our expectation is that that's going to continue to happen into Q4. And, you know, we've got a continuous improvement program that continues to drive productivity and efficiency gains. And, you know, we're expecting that and, you know, to combat some of these inflationary pressures as well as continuing to deliver to our customers. And we'll continue to do that into 22 as well. Great.
Jack Meehan
And then one other follow-up is on COVID. So the fourth quarter guidance assumes it's a one-point headwind, though we're obviously in the middle of another delta wave here. So I was curious what you're seeing on the ground or whether, you know, your products are just starting to wane in general and any preliminary thoughts around how, you know, you have $100 million this year, just how you're going to guide as you go into 2022 related to that?
Tachi Yamada
Yeah, you know, what I would say, Jack, is a good question. And, you know, our products aren't, you know, directly tied to the testing. We didn't see the dramatic increase, but also didn't see the dramatic declines with the testing there. Ours is more around expanding capacity, both in testing and over this course of this last year, we've actually seen it migrate to more therapeutic capacity, or excuse me, vaccine capacity and demand there. And so we don't see it, you know, spiking up. We're not building that into the Q4. I think it's a little too early to tell for FY22. You know, it's been recent. reasonably steady the last couple of quarters and we do expect contribution in 22 um uh and uh we'll provide more color you know as we get through our our planning process but we don't see it dramatically dropping off sounds good thanks Bob yep I do apologize but we do have an additional question the last question is from Dan Arias with Steve your line is open
Patrick Dinelli
Yeah, hi, guys. Thanks for getting me in here at the end. Hey, Mike. Sure, no problem. Just one for me. Just, Bob, maybe a high-level question, just sort of to the idea of getting to a post-COVID world, whenever that might be. I'm wondering which of the three segments you think might stand the best chance of maybe rebasing at a higher level at the op margin line, just by virtue of some of the success that you're having, and then to your point, some of the fundamental changes that might come to the expense structure. I mean, is that something you think is possible? And if so, would you be willing to sort of help us with which one is looking most promising there?
Tachi Yamada
Yeah, I do think it's possible. I'm not going to call out because I'm not going to let – if I call out one, I'm not going to let the other two division presidents off the hook. They must have paid you. I think we could continue to do it across the board. Certainly, you know, we are making investments across all three of the businesses to continue to grow, but – We certainly feel like we have opportunities to continue to drive margin enhancement across all three of our business groups. Sorry, guys.
Paul
Okay. Thanks, Paul. Thanks, Dan.
Operator
And that concludes the question and answer session for this conference call. I will now turn the conference back to Parmeet Ahuja for closing remarks.
Ahuja
Thanks, Paul, and thanks, everyone. With that, we would like to wrap up the call for today. Have a great rest of your day.
Operator
Ladies and gentlemen, this concludes today's conference call. Thank you for joining Humanities Connect. Stay safe and well.
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